2000 - sept - paper 1 and 2

Discussion in 'MRCOG Forum' started by Guest, Feb 15, 2005.

  1. Guest

    Guest Guest

    sept 1 2

    1 FFTFF TFT?_T
    2 FFFTF TFTTT
    3 FTTFF TFT?TT
    4 TTFFF
    5 TFFFT TTTTT
    6 FFTTT TTFTT
    7 FTTTF FFTTT
    8 TTTFF FTTTF
    9 FFTFT TFTFF
    10 FFTTF FFTTF
    11 FFTTT TTTTF
    12 FFFFT TTTFF
    13 FFFTT FFTFT
    14 TTFTF F?FFFF
    15 TFTFT FFFTT
    16 FFTFF TFTTT
    17 TTTFT FFFFT
    18 TTFTF TTFTF
    19 TTFTF FTFFT
    20 FT?TFT TFTFF
    21 TFTFF FFTFF
    22 TTTFT TTFFT
    23 FTFTT TTFFT
    24 TFTFT FFTFT
    25 TTFTF TTTFT
    26 FFFTT TTFTT
    27 TFFTF FTFFF
    28 TFTFF TFFTT
    29 FFFF?F TTFFT
    30 FTTTF TTTFT
    31 FFTTF FFTFF
    32 TFFTF FTFTT
    33 FFTFF TTTTT
    34 TTTFF FTTTT
    35 TTTTF TTFFF
    36 FTFTT TFFTT
    37 TFFFT TFTFF
    38 TFTFF TTFFT
    39 TTFFT FTTTT
    40 TFFFT FTFTF
    41 TTTTF FTFTF
    42 TFFFF TTTTT
    43 FTTTT FFFFT
    44 FFTTT TTFTT
    45 FTFTF TFTTT
    46 TFTTT FFTFF
    47 FTFFT FTTFF
    48 FTFFT FTTFF
    49 FTFFT TTFFT
    50 FTFFF TFTTF
  2. Shipra

    Shipra Guest

    In Q-47, paper-2 'c' shd be false as it is 3500 ml.
  3. Shipra

    Shipra Guest

    paper-2 q33 are u sure abt 'd' as i couldn't find it anywhere??
  4. Shipra

    Shipra Guest

    paper-2 39 'b' shd be false as its not a voluntary but reflex contraction...only striated muscle can lead to voluntary contraction
  5. Shipra

    Shipra Guest

    Q-4 paper-2 -- cde shd be true
  6. shipra

    shipra Guest

    paper-2 1'd' shd be true
  7. Shipra

    Shipra Guest

    paper-2 Q2 'b' shd be true. Products formed as a result of enzymatic reaction may accumulate and it may lower the enzymatic reaction by occupying the active site on the enzyme.
  8. Shipra

    Shipra Guest

    paper-2 Q18 'b' sjd be false. X( sex) linked disorders are different from disorders of sex chromosome. Sex chromosomes carry gene resposible for determination of sex; they also carry other genes that control other characters that have nothing to do with sex....this is known as sex linked inheritance. eg haemophilia,color blindness,muscular dystrophies,retinitis pigmentosa,G6pd def. , vit D resistant rickets,fragile X syndrome.
  9. Shipra

    Shipra Guest

    paper-2 ,11'b' shd be false. Pls verify.
  10. Guest

    Guest Guest

    pls give me some time, wil get back (not well)
    thx
  11. Guest

    Guest Guest

    paper-2 q33 are u sure abt 'd' as i couldn't find it anywhere?? - i couldnt either - discussed with doctorsin medicine, they said it can??

    paper-2 39 'b' shd be false as its not a voluntary but reflex contraction...only striated muscle can lead to voluntary contraction - u sound right. agree

    Q-4 paper-2 -- cde shd be true - agree.
    whats ur answer for 4 b??? i amnot sure abt that answer??

    paper-2 1'd' shd be true - agree

    paper-2 Q2 'b' shd be true. Products formed as a result of enzymatic reaction may accumulate and it may lower the enzymatic reaction by occupying the active site on the enzyme. - thx for the correction

    paper-2 Q18 'b' sjd be false. X( sex) linked disorders are different from disorders of sex chromosome. Sex chromosomes carry gene resposible for determination of sex; they also carry other genes that control other characters that have nothing to do with sex....this is known as sex linked inheritance. eg haemophilia,color blindness,muscular dystrophies,retinitis pigmentosa,G6pd def. , vit D resistant rickets,fragile X syndrome. - thx for that, agree

    paper-2 ,11'b' shd be false. Pls verify. - i have read it somewher that it does bind. will coem back with reference later. (had looked for this answer, just cant rememebr now where??!!). for now , it binds to hormones, metals, ions, Fatty acids, amino acids, enzymes and drugs other than those mentioned.
  12. Guest

    Guest Guest

    PAPER 2
    Q-38 d - do u agree with false?

    paper 1 - 41 e - do u agree with false?
  13. Shipra

    Shipra Guest

    38-d paper-2 is false....phosphatidyl glycerol wud be a phospholipid...
  14. Shipra

    Shipra Guest

    41-e paper-1 agree with false...as I couldnt find anywhere such drug interaction
  15. Shipra

    Shipra Guest

    paper-2,Q24 -- 'c' shd be false as macrophages and dendritic cells do this function...pls check.
  16. Shipra

    Shipra Guest

    paper-1 3'e' shd be true
  17. Shipra

    Shipra Guest

    In paper-1 ,49 'c' shd be true...as n is always greater than 1.
  18. Shipra

    Shipra Guest

    paper-1 , 39- 'b' 'e' shd be false. only 'a' is true.
  19. Shipra

    Shipra Guest

    Paper-1- 37 'c' shd be true and 'a' shd be false.
  20. Shipra

    Shipra Guest

    Paper-1 -38 'b' shd also be true
  21. Shipra

    Shipra Guest

    Paper-1 43 'd' shd be false as its given only for 5 days generally between day 2 to day 6 of the cycle.
  22. Shipra

    Shipra Guest

    Paper-1 44 'e' shd be false as phenoabrb induces its metabolism...hence decreases its action
  23. Shipra

    Shipra Guest

    paper-2 46 'e' shd be false as halothane causes bronchial dilatation hence is preferred for asthamatics...
  24. roni

    roni Guest

    B lymphcytes can do this fuction read it somewhere not sure where? :!:
  25. Guest

    Guest Guest

    Halothane

    Regarding Paper1, Q 46,
    In the text book clinical pharmacology
    Isoflurane, casuses irritation of the upper airway, although it is a bronchodilator
    but nothing is written about Halothane irritation but it is mention that it has a pleasant smell
    if you check this website
    http://www.nda.ox.ac.uk/wfsa/html/u11/u1115_02.htm
    you will find that one of the advantages of Halothane that it is non-irritant

    so I would consider it false...

    Regards..
    Dr. Mohamed A. Otify
  26. violet

    violet Guest

    comments on paper 1 2000 sept

    Hello Ruby and Shipra,

    At the moment I've done paper 1 2000 (sept). I 've got few queries.

    I agree with E. false for Q. 41 (paper - 1), although could'n find anywhere hard evidences.

    Q.3 E should be true as pituitary gland entirely ectodermal in origin

    Q.6 D should be false as obturator nerve lies above obturator artery in obturator foramen

    Q.16 E should be true

    Q.17 A should be false as thyroxine part of thyroglobulin in colloid of thyroid follicles.

    Q.17 D should be true as amount of two unbound thyroid hormones approximately the same.

    Q.24 B should be true, HCG is biochemically indistinguishable from LH

    Q.24 C should be true, HCG active in non-pregnant women

    Q.27 B should be true, vasopressin is polypeptide

    Q.38 B query true?

    Q.43 D should be false

    Thanks
  27. Guest

    Guest Guest

    Re: comments on paper 1 2000 sept


    Q17 D the total free of T4 is 25 pmol/l whereas of T3 is 5pmol/l, so i think it should be false.

    Q24 B not sure but i think they are similar but not identical someone has 30 amino acids more than the other.(comment please)
  28. Shipra

    Shipra Guest

    Also...paper-1 34 'c' shd be false as causative agent of sleeping sickness is trypanosoma Gambiense.
  29. Shipra

    Shipra Guest

    Hi violet,

    About Vasopressin...its an octapeptide....not a polypeptide ( note if there are more than 50 aminoacid residues then its a polypeptide...while AVP has only 8 a/a residues)
  30. Shipra

    Shipra Guest

    17d shd be false as 0.03% of t4 and 0.3% of T3 ( approx values) are free ....so t3 is nearly 10 fold the free conc of t4....which is a big difference.

    HCG alpha subunit is identical to LH ( ref ganong) so I'd go for true.

    Rest other ans I agree with u violet.
  31. Shipra

    Shipra Guest

    paper-1 17'e' shd be false I think...as thyroid hormone is transported across placenta in very minimal amounts....pls someone comment..
  32. Shipra

    Shipra Guest

    paper-1 9'c' shd be false...
  33. Guest

    Guest Guest

    Correction

    just wanted to correct...
    Vasopressin is a Nona-peptide (9 amino acids)

    HCG is biochemically indistinguishable from LH , is a false statement, sure both alpha subunits are idential which goes for som more hormoens which share teh same Alpha subunit but they differ in Beta subunit... that means they have different moelcular weights, which makes them different biochemically, thats my opinion


    Dr. Mohamed A. Otify
  34. Shipra

    Shipra Guest

    Agreed with the above post..
  35. violet

    violet Guest

    comments

    I agree with this statement, possibly active, doesn't mean actively! I'll go for false. Agree with rest.

    Anothe q. where did you find that polypeptides are content 50 or more AA, I intepreted it differently, vasopessin - is nonapeptide (Tim Chartd, p. 102), therefor it is a polypeptide?

    What do you say?
  36. Shipra

    Shipra Guest

    I read it in my biochem text....besides Ruby has also quoted something like this in 99 march paper 1 & 2....
  37. Guest

    Guest Guest

    hi shipra,
    paper-1 3'e' shd be true - agree
    paper-1 ,49 'c' shd be true...as n is always greater than 1. -it is true - agree
    paper-1 , 39- 'b' 'e' shd be false. only 'a' is true. - agree
    Paper-1- 37 'c' shd be true and 'a' shd be false. - agree with a beign false. will reconfirm c
    Paper-1 -38 'b' shd also be true - false, CBG rises - so free should decrese, pls reconfirm
    Paper-1 43 'd' shd be false as its given only for 5 days generally between day 2 to day 6 of the cycle.- ur right, thx for correcting that
    Paper-1 44 'e' shd be false as phenoabrb induces its metabolism...hence decreases its action- i think phenobarbitone is an enzyme inducer, so enhances drug action, pls reconfirm with de sweit and correct me if i am wrong

    paper-1 46 'e' shd be false as halothane causes bronchial dilatation hence is preferred for asthamatics...- u r right, its false - its non-irritant http://www.frca.co.uk/article.aspx?articleid=278

    Also...paper-1 34 'c' shd be false as causative agent of sleeping sickness is trypanosoma Gambiense. - agree, thx for the corrxn
  38. violet

    violet Guest

    In Ganong page 97 there is a table of neurotransmitters and neuromodulators and under Polypeptides is Vasopressin


    Thx
  39. Shipra

    Shipra Guest

    Here is what I found in Ganong-

    " The boundaries between peptides,polypeptides and proteins are not well defined,but in this book,chains containing 2-10 aminoacid residues are called peptides,chains containing more than 10 but fewer than 100 amino acid residues are called polypeptides and chains containing 100 or more amino acid residues are called proteins. The term 'oligopeptide' which is used by others to refer to small peptides is not used."( I think Ruby too gave this piece of info.)

    Hence...in no case nonapeptide can be a polypetide...I think so... :roll:
  40. Guest

    Guest Guest

    agree with u shipra
  41. Shipra

    Shipra Guest

    paper-1 38 'b'-- agreed with you..actually free cortisol index rises...got confused with that... :oops:
  42. Shipra

    Shipra Guest

    paper-1 44'e'- Well u r right...phenobarbitone is a hepatic enzyme inducer hence induces the metabolism of warfarin thereby reslting into decreased anticoagulant action...same is true for other hepatic enzyme inducers like rifampin,griseofulvin.I am quoting it from my pharmac text.Pls tell me if u find anything anywhere otherwise....
  43. shipra

    shipra Guest

    so acc. to me ans shd be false
  44. Guest

    Guest Guest

    hi violet,
    Q.3 E should be true as pituitary gland entirely ectodermal in origin - agree
    Q.6 D should be false as obturator nerve lies above obturator artery in obturator foramen - agree
    Q.16 E should be true - thx for correcting me
    Q.17 A should be false as thyroxine part of thyroglobulin in colloid of thyroid follicles. - ?
    Q.17 D should be true as amount of two unbound thyroid hormones approximately the same. - has already been discussed onthe forum
    Q.24 B should be true, HCG is biochemically indistinguishable from LH - i am not sure abt this - are sure?
    Q.24 C should be true, HCG active in non-pregnant women - i agree
    Q.27 B should be true, vasopressin is polypeptide - already discussed on forum
    Q.38 B query true? - ???
    Q.43 D should be false [/i][/color] -[/i][/color] - it is false
    thx
  45. Guest

    Guest Guest

    paper-1 44'e'- Well u r right...phenobarbitone is a hepatic enzyme inducer hence induces the metabolism of warfarin thereby reslting into decreased anticoagulant action...same is true for other hepatic enzyme inducers like rifampin,griseofulvin.I am quoting it from my pharmac text.Pls tell me if u find anything anywhere otherwise....

    its an enzyme inducer that inhibits enzymes catalyzing the drug - therefore enhancing the drug in questions effect. its there in de sweit too In pharm chapter under heading of enzyme inducers..
  46. Shipra

    Shipra Guest

  47. Shipra

    Shipra Guest

    Pls see 13th column
  48. Shipra

    Shipra Guest

    Q1 paper-1 ,'e' can be true...as int pudendal is also one of the arteries that take part in formation of anastomosis to form ant and post azygous arteries which finally supply whole vagina...pls comment.
  49. Guest

    Guest Guest

    hey, u right abt the inducer - i was wrong :cry:
  50. Guest

    Guest Guest

    Q1 paper-1 ,'e' can be true...as int pudendal is also one of the arteries that take part in formation of anastomosis to form ant and post azygous arteries which finally supply whole vagina...pls comment. - agree

    art supplying superior part of vagina: from uterine A
    middle : vaginal art
    inferior part: middle rectal and internal pudendal artery

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