2001 - sept 2001 - paper 1 and 2

Discussion in 'MRCOG Forum' started by Guest, Feb 15, 2005.

  1. Guest

    Guest Guest

    sept 1 2

    1 TTFFT TTTFT
    2 TFFTT TFTFT
    3 TFFFT TFT?TT
    4 FFFFT TFT?TF
    5 FFTTF TFTFT
    6 FFTFT TTTFT
    7 FTTTT FFFFF
    8 FF?TFF TTTTT
    9 TFTFT FTFFT
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    11 FFFTF TTFTF
    12 FTFTF FTFFF
    13 TTTFT FTTTT
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    15 FTFFT FFFFT
    16 FTTTT TTFFT
    17 TTFTT TFTFT
    18 FTFFT ?TT?FFF
    19 TFTT?F FFFFT
    20 FFFFT TFTFT
    21 TFFTT TTFFF
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    23 TTFTF FTTFF
    24 TFFTF TTTFT
    25 FFFTF TTTFT
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    27 TFFFF TTTTT
    28 FFFTT TTTTT?
    29 TTFTF TTTFT
    30 TTTFT FTTTF
    31 FT?TFF FTFFT
    32 FTFTT FTTFT
    33 TFTTT FTFTF
    34 TFTFF FTTTF
    35 FTFTT FTTTF
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    37 TFTFT TTTTF
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    40 F?_TTT TTTFF
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    44 FTFFF TTTFF
    45 FTTFT TTTFF
    46 FFTTF TFTTT
    47 TFTTT FFFFT
    48 FFTFT FTTFF
    49 TFFFF FTTFF
    50 FFFTF FTTTF
  2. kavitha

    kavitha Guest

    fr past qst

    hello rubyruprai,
    i would be pleased if u send the past qts .my mail id is kavithau@yahoo.com.thanks fr ur prompt reply.
  3. Guest

    Guest Guest

  4. Shipra

    Shipra Guest

    Q46- paper-2.-- urine ph falls during normal pregnancy.... ans shd be false,,,,,as urinary ph becomes alkaline in pregnancy...hence uti is common in pregnancy...pls comment
  5. Guest

    Guest Guest

    hi.
    this seems a tricky question: the normal urine ph has a wide range: 4.5 - 8
    also, in pregnancy the change in ph doesnot predispose the woman to developing uti- imp causes of uti are due to dialtation of urinary tract and vesicouretral reflux. i am not too sure but if one has to consider increase bicarbonate loss in urine (secondary to hyperventilation) then perhaps es, the urine does become more alkaline??!!
  6. Shipra

    Shipra Guest

    In paper-2 Q-45 -- serotonin is vasodilatory is true... arteries are both constricted as well as dilated ( thru EDRF release) ....effect is actually variable depending on vascular bed and basal tone...for eg Sumatiptan a serotonin antagonist is helpful in migraine which is actually pulsatile dilatation of cranial vessels due to excess serotonin....does it sound logical..??
  7. Shipra

    Shipra Guest

    In paper-2 Q 44. -- total body water is predominantly intracellular-- shd be true.
  8. Guest

    Guest Guest

    u r right - pls correct the same for sept 1998 paper 2 q 47
    thx
  9. Shipra

    Shipra Guest

    Q42- paper-2 option d should be false as alpha 1 receptor stimulation leads to mydriasis.
  10. Guest

    Guest Guest

    alpha adr stimulation leads to constrn
    beta leads to dilatation
    cholinergic also leads to constrn
    (ref: de sweit - basic sciences)
  11. Shipra

    Shipra Guest

    Thanx for explanation....I had some other book in which I found the other way round...but we shd follow the books recommended...

    one more doubt...Q-37,paper -2 -- option b shd be false.Pls check.
  12. violet

    violet Guest

    Option B

    Hi Shipra! I made this paper as well. Q-37, paper -2, 2001.

    T, F, F, F, F.
    B. A2 >2,5%
  13. Guest

    Guest Guest

    hi,
    sorry abt that
    u both right
    hba2 definitely increases!
  14. Shipra

    Shipra Guest

    Hi Violet,
    I think C and D shd be true in ur ans
  15. Shipra

    Shipra Guest

    In Q 31, paper-2 ,option c shd be true. pls comment.
  16. Guest

    Guest Guest

    HI,
    I initialy thought it was true , but after i discussed it with orthopedicians, they said its not!!? i am not too sure
  17. violet

    violet Guest

    correction

    I agree that D is true, there is no information regarding increasing of HbF in this condition. Do you have a reference?
  18. Shipra

    Shipra Guest

    What I found in my texts is-- there's both abnormal osteoclastic as well as osteoblastic activity in rickets.Osteoblasts are responsible for deposition of matrix and subsequent calcification.In rickets,osteoblast proliferation does not take place in an orderly fashion and isn't accompanied by vascularisation and mineralisation....
  19. Shipra

    Shipra Guest

    Hi violet,

    The increase in HbF is marked from normal 1% to about 96 %. U may find it in any of the medicine texts
  20. Guest

    Guest Guest

    thx,
    i was trying to google thru some articles now for this. u saved me time! and i agree with u, but what are ur referenes dear?
  21. violet

    violet Guest

    correction

    Sorry, I read a question incorrectly.... Agree!
  22. Shipra

    Shipra Guest

    Hi Ruby,
    In Q -28 paper -2. e is true.. I found it in my text of biochem and tumor marker is CEA...but I m not sure ab't option 'a'. U marked it as true. Do u know what's the blood marker in clear cell carcinoma....?
  23. Guest

    Guest Guest

    hi shipra,
    i had read ca 125 to be a blood marker for clear cell ca (and ca 125 is not specific., but i am unsure of the ansers to all except b and e for the reason that they have asked for characteristic blood markers inthe question.
    likewise, some say alp is the marker for osteogenic sarcoma, but thats not what the docs here believe. (its like how we use ca 125 for ep ov tumors). they say it is false coz its not characteristic.
    also, i read for transitional cell tumor that the marker is some p.. something. didnt come across cea??!!?
    what do u feel??
  24. violet

    violet Guest

    Q.31

    My answers q.31. F, T, T, T, T
  25. Shipra

    Shipra Guest

    Ruby,
    In Q20,paper-2 , u have marked 'e' as true....is it in severe hypospadias ,genotype is not male....?? I mean it's not a condition like adrenogenital syndrome or potter's syndrome..it's simply a manifestation...Can u pls explain? Thanx.
  26. Shipra

    Shipra Guest

    Also in Q 15,paper -2.... isn't option b - treatment with spironolactone true..??
  27. Shipra

    Shipra Guest

    And in Q-12 paper -2, option 'c' -- mRNA is not present in reticulocyte should be true as these cells are anucleated and hence nucleic acids are absent in them...however they do have ribosomal rna which is present in cytosol.Pls check.
  28. Shipra

    Shipra Guest

    In Q -18,paper-2-- 'c' can be true as e is also an antigen and thus is capable of inducing antibody formation....though D is most antigenic.
  29. Shipra

    Shipra Guest

    In Q-17,paper-2 a,b,e shd be true and c ,d shd be false. Skin receives greater dose of radiation that's why we calculate sq. cm area in radiation.Major effect of radiation is to damage the nucleus of any cell.( Ref: Robbins)
  30. Shipra

    Shipra Guest

    In Q-13, paper-2, only c and e are true; rest are false. Most of reactions of glycolysis occur in extra mitochondrial cytosol as most of the glycolytic enzymes are located there. And there's a net gain of 8 ATP mol in coversion of glucose to pyruvate.
  31. Shipra

    Shipra Guest

    Sorry net gain of 2 ATP so ans is true...sorry ab't that.
  32. Shipra

    Shipra Guest

    In paper-2, Q -5 , ABO antigens are MHC antigens... u marked it true...but can u pls quote the ref as I couldn't find it anywhere.MHC -1 antigen is present in cell surface of all nucleated cells...and rbc's are anucleated. And MHC - 2 antigens are found in cells of only immune system...can u pls explain..thanx
  33. Shipra

    Shipra Guest

    In paper-2--Q-4 --plasma clearance rate of creatinine is equivalent to renal plasma flow shd be false as it gives GFR. And PAH is used to calculate renal plasma flow as its clearance is equal to renal plasma flow.
  34. Guest

    Guest Guest

    hi shipra, sorry had logged out last evening. have gone thru ur questions; will answer few now and will confirm the others andget back:
    mRNA
    In vivo, reticulocytes are highly specialized cells primarily responsible for the synthesis of hemoglobin, which represents more than 90% of the protein made in the reticulocyte. These immature red cells have already lost their nuclei, but contain adequate mRNA, as well as complete translation machinery, for extensive globin synthesis.

    spironoloactone - does spare potassium - but its the characteristic word that puzzles me!

    reg hypospadiasis - they say in condts that donot correlate with phenotype - here although genotype is that of male, in severe case at birth it may present as ambiguous genitalia

    reg cDE antibodies - i agree with ur answer

    reg. radiation - i gree with the activity on nucleus bit - i think i wrongly typed it as true for cytoplasm - effect is primarily on nucleus. however, for the skin part - i am not too sure as if that were the case then we would have had skin damage/ manifestations for the actual target being inside the body and we dont see that in clinical practice!?

    reg glycolysis - u r right abt the site! me wrong :( - my biochem is weak!!! pls look into my other mistakes too and let me know

    wil get back on MHC

    reg creatinine- i feel since creatinine is neither secreted nor reabsorbed, and is present in plasma, the clearance should be = renal plasma flow - what say u? can u pls refer ganong and tell me what u understand fromthere on this, coz thisis what i understood
  35. roni

    roni Guest

    sorry for interrupting

    but creatinine clearance is the same as GFR which is entirely different than the renal plasm flow because not all the renal flow is filtered so that' why we use the filtration fraction.

    and if the concentration of creatinine in the venous blood was zero then you can say that it's clearance is equivalent to the renal plasma flow.

    again i cannot pretend to be 100% sure but this is what i know about those things.
  36. Guest

    Guest Guest

    thx roni,
    what u say sounds right, but because there is a confusion, can u pls be kind enough to just tell me what u understand of this in ganong - coz the more i read, the more confused i get and brain is clouded!! :wink:
    thx -will wait for ur reply
  37. Guest

    Guest Guest

    hi shipra -
    i think ur right on ABO antigens - they are separate form MHC and red cells lack MHC
    class I antigens, major histocompatibility antigens found on virtually every cell, human erythrocytes being the only notable exception

    class II antigens, major histocompatibility antigens found only on immunocompetent cells, primarily B lymphocytes and macrophages

    class III antigens, a term used to refer to nonhistocompatibility antigens mapping in the major histocompatibility complex, e.g., the complement components C2, C4, and factor B.
  38. RONI

    RONI Guest

    I studied those parts from de swiet alone and i think they are very simple and easy

    sometime we shouldn't confuse our brains with huge resources and the small ones seem to be much of a help especially in times of scarcity (regarding time ofcourse).

    Sincerely yours
    roni
  39. Guest

    Guest Guest

    shipra to ur doubt on relation of ant portion of supravaginal cervix - ureter is not realted - just confirmed it!!
    The cervix consists mostly consists of fibrous tissue two components, supravaginal vaginal portions. The supravaginal portion separated in front from bladder by fibrous tissue (parametrium), which extends also on its sides lateralward between layers of broad ligaments. The uterine arteries reach margins of cervix in this fibrous tissue, while on either side ureter runs downward forward in it at a distance of about 2 cm. from cervix. Posteriorly, supravaginal cervix covered by peritoneum, which prolonged below on posterior vaginal wall, when it reflected on rectum, forming rectouterine excavation. It lined by columnar stratified squamous epithelium (vaginal portion).
  40. Shipra

    Shipra Guest

    Thanx Ruby...
  41. Shipra

    Shipra Guest

    In q-4.paper-1 -- option 'b' shd be true ....as whole hypophysis is derived from ectoderm...though sites from where both parts dev are different. Posterior pitutary develops as a downgrowth from 3rd ventricle...which is ectodermal ( whole CNS is ectodermal in origin). Correct me if I m wrong pls.
  42. Shipra

    Shipra Guest

    In Q-19 paper-1 -- option 'c' and 'e' shd be false . There occur 2 peaks in secretion of estrogen during the normal ovarian cycle,one is just before ovulation that is,just before 14th day and next in mid luteal phase which is ofcourse more than 14th day....so it can't be 8th day. And...though stromal tissues of ovary are also capable of producing oestrogen,they aren't the primary source, theca interna and granulosa cells are the primary source. ( Ref: Ganong)
  43. Shipra

    Shipra Guest

    In paper-1 Q -27 -- 'd' shd be true . The growth promoting , nitrogen retaining and certain metabolic actions of GH are exerted indirectly through elaboration of peptides called Somatomedins or Insulin like growth factors ( IGF-1, IGF-2) which are extracellular mediators of growth hormone response
  44. Shipra

    Shipra Guest

    In Q-36, paper-1... option'c' shd be false as mycobacteria are aerobes.
  45. Anamika

    Anamika Guest

    mrcog papers

    Hi rubyruprai,
    Will you please please send me the papers you have been discussing, on the following ID--anamika97123@rediff.com.By the way how are you getting these papers?
    Thanking you in anticipation.
  46. Shipra

    Shipra Guest

    Hi Anamika,

    I've bought past paper book from RCOG , bought it from amazon .co.uk
  47. Guest

    Guest Guest

    HI ANAMIKA -
    bought he book online at the official rcog wbsite -www.rcog.org.uk - bookshop
    or otehr option is to buy the way shipra did.
    rgds
  48. Guest

    Guest Guest

    hi shipra,
    u right abt insulin like growth factor and embryonic origin of pituitary being ectodermal. thx for correctingmy mistake(S).

    reg, estrogen peak - will refere ganong and correct myself - thought i read the day 8 part somewhere. u also reight abt the ov stroma being a source - though not primary. primary woudl be granulosa cell - follicular but theca for circulating estradiol levels.

    mmmm.... what else did u ask - yeah - myco bacteria are also facultative anaerobes and not all are pathogenic in humans (esp atypical ones).
  49. Shipra

    Shipra Guest

    Ruby I agree with u on the point that not all mycobacteria are pathogenic...but can u pls reconfirm the statement mycobacteria are facultative anaerobes...as I couldn't find it anywhere even in atypical mycobacteria....atypical mycobacteria are so named because of their slow growth rate,antibiotic resistance,pigment producing properties and ubiquitous distribution...so can u pls quote ur reference? Thanx.
  50. Guest

    Guest Guest

    mmm... ref is the diffcult part. will tell u for sure in a days time as i will have to find out myslef - but its also peer discussion (with medicine doc and microbiologist). gimme some time on this.
    thx

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