A 3-year-old boy with cystic fibrosis is evaluated for the a

Discussion in 'USMLE STEP 1' started by Guest, Dec 22, 2009.

  1. Guest

    Guest Guest

    A 3-year-old boy with cystic fibrosis is evaluated for the acute onset of an uncontrollable nosebleed. There is no family history of a bleeding disorder. A few large bruises are seen on the legs; no other abnormalities are noted. Prothrombin and partial thromboplastin times are prolonged. The patient's abnormalities are likely to improve with treatment using a cofactor for which process?

    A) Carboxylation of prothrombin

    B) Conversion of homocysteine to methionine

    C) Farnesylation of ras

    D) Hydroxylation of procollagen

    E) Phosphorylation of pyruvate dehydrogenase
  2. Guest

    Guest Guest

    Carboxylation of prothrombin

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