A 32 year old man has had malaise, a low grade fever, and a

Discussion in 'USMLE STEP 1' started by Guest, Jun 10, 2010.

  1. Guest

    Guest Guest

    A 32 year old man has had malaise, a low grade fever, and a 4.5 kg weight loss over the past 3 months, he has unilateral cervical lymphadenopathy. Lab shows Hb 11g/dl; Hct 33%; mean corpuscular volume 80 um3; reticulocyte count 0.5% Serum iron 25 ug/dl; total iron binding capacity 150 ug/dl (N=250-460) Examination of tissue obtained on biopsy of a lymph node shows Hodgkin’s disease, nodular sclerosing type, the most likely cause of the anemia is
    a. abnormal utilization of iron
    b. extravascular hemolysis
    c. folate deficiency
    d. iron deficiency
    e. marrow aplasia
  2. Guest

    Guest Guest

    A .
    'cos of abnormal storage of iron in bone marrow macrophages[anemia of chronic dx].

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