A 63-year-old woman notices lumps on both sides of her neck

Discussion in 'MRCS Forum' started by Enabel., Mar 20, 2008.

  1. Enabel.

    Enabel. Guest

    A 63-year-old woman notices lumps on both sides of her neck. A fine-needle aspiration (FNA) is carried out and the diagnosis is made of Hurthle cell carcinoma of the thyroid. Correct statements concerning Hurthle cell carcinoma of the thyroid include which of the following?
    a- It is a from of Anaplastic thyroid cancer
    b- It metastasizes via the lymphatics to regional lymph node basins
    c- Treatment consists of a near-total (or total) thyroidectomy
    d- Microscopically, it consists of clusters of cells separated by areas of collagen and amyloid
    e- Once treated appropriately, it has a low rate of recurrence
  2. Enabel.

    Enabel. Guest

    Answer: c. (Schwartz, 7/e, pp 1685-1686) Hurthle cell cancer is a type of follicular cancer, but it tends to recur more often than other types. Follicular cancer spreads hematogenously to distant sites. This is unlike papillary cancer, which metastasizes via the lymphatics. Amyloid deposits in the stroma of a thyroid tumor are diagnostic of medullary carcinoma. The treatment of choice is a near-total thyroidectomy to facilitate later body scanning for metastases and treatment with 131I.

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