A peripheral blood smear shows normocytic, normochromic red

Discussion in 'USMLE STEP 1' started by Guest, Jun 13, 2010.

  1. Guest

    Guest Guest

    A 35-year-old male presents to his physician complaining of two weeks of fatigue and easy bruising. He also reports recently having had an upper respirators tract infection. Physical examination reveals no lymphadenopathy or hepatosplenomegaly.

    Laboratory studies show:

    Complete blood count
    Hemoglobin....................... 7.0 g/L
    Erythrocyte count.............. 1.8 min/mm3
    Mean corpuscular volume... 90 fl
    Reticulocytes..................... 0.1%
    Platelet count.................... 88000/mm3
    Leukocyte count................ 2500/mm3
    A peripheral blood smear shows normocytic, normochromic red blood cells. The other cell types are morphologically normal as well. Bone marrow biopsy in this patient would most likely show which of the following patterns?

    A. Hypocellular marrow filled with fat cells and fibrotic stroma
    B. Hypercellular marrow with megaloblastic hematopoiesis
    C. Hyper granular promyelocytes with multiple Auer rods
    D. Hypercellular marrow filled with numerous blast forms
  2. Guest

    Guest Guest

    It is aplastic anemia because
    1. Retic ct is low

    2. If infiltrative or dysplastic anemia, abnormal cells- teardrop cells-anisocytosis,poikilocytosis should be found.

    3. If leukemia, blast forms(myeloblasts) of cells should be present.

    4.If myelodysplastic syndrome, dyserythropoeitic cells should be present

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