A publication reports the outcome of a new statin therapy in a placebo controlled pri

Discussion in 'MRCP Forum' started by Santosh Jadhav, Nov 8, 2013.

  1. Santosh Jadhav

    Santosh Jadhav Active Member

    Question: 57

    A publication reports the outcome of a new statin therapy in a placebo controlled primary
    prevention study of ischaemic heart disease in a diabetic population.
    1000 patients were randomised to receive the new therapy and 1000 allocated to placebo.
    The study was completed over a five year period. In the placebo group there were 150
    myocardial infarcts (MIs) and in the group treated with the new statin there were 100 infarcts.
    What is the annual percentage of myocardial infarction in the diabetic population treated with
    placebo?
    (Please select 1 option)
    1%
    3%
    5%
    7%
    10%

    This study shows that there are 150 MIs in 1000 diabetic patients treated over a five year
    period in the placebo group.
    Hence the rate of infarction in this group is 150 / 1000 = 15%, divided by 5 years to give the
    annual MI rate of 3%

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