ACQUIRED HEMOPHILIA

Discussion in 'AIIMS Nov 2013' started by samuel, Aug 21, 2014.

  1. samuel

    samuel New Member

    ACQUIRED HEMOPHILIA:

    Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies directed against plasma coagulation factors, most frequently factor VIII

    The following conditions may be associated with acquired hemophilia A

    Idiopathic
    Pregnancy
    Autoimmune disorders
    Inflammatory bowel disease, ulcerative colitis
    Dermatologic disorders (eg, psoriasis, pemphigus)
    Respiratory diseases (eg, asthma, chronic obstructive pulmonary disease)
    Allergic drug reactions
    Diabetes
    Acute hepatitis B infection
    Acute hepatitis C infection
    Malignancies-solid tumors (prostate, lung, colon, pancreas, stomach, bile duct, head and neck, cervix, breast, melanoma, kidney)
    Hematologic malignancies

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