ALL INDIA PRE PG EXAM 2009 Questions with Answers

Discussion in 'NEET 2013 All india Exam' started by Guest, Jan 13, 2009.

  1. twinkle.

    twinkle. Guest

    risk factors for gall bladder cancer a/e
    ans: polyp more than 5mm
    its actually polyp size more than 10mm

    ref: as in schwartz
    Approximately 90% of patients with carcinoma of the gallbladder have gallstones. However, the 20-year risk of developing cancer for patients with gallstones is less than 0.5% for the overall population and 1.5% for high-risk groups. The pathogenesis has not been defined but is probably related to chronic inflammation. Larger stones (3 cm) are associated with a tenfold increased risk of cancer. The risk of developing cancer of the gallbladder is higher in patients with symptomatic than asymptomatic gallstones.
    Polypoid lesions of the gallbladder are associated with increased risk of cancer, particularly in polyps larger than 10 mm. 66 The calcified "porcelain" gallbladder is associated with more than a 20% incidence of gallbladder carcinoma. These gallbladders should be removed, even if the patients are asymptomatic. Patients with choledochal cysts have an increased risk of developing cancer anywhere in the biliary tree, but the incidence is highest in the gallbladder. Sclerosing cholangitis, anomalous pancreaticobiliary duct junction, and exposure to carcinogens (azotoluene, nitrosamines) also are associated with cancer of the gallbladder.
  2. drusti.

    drusti. Guest

    culture media for e.coli 157:eek:7
    a.xld agar
    b.?
    c?
  3. twinkle.

    twinkle. Guest

    unilateral nasal stuffiness is a feature of stellate ganglion block..the ans is bradycardia

    Patients usually develop Horner’s syndrome and Guttman’s sign, stuffy nose and increased temperature on the ipsilateral side of the block (face and upper extremity) within 5 min of block
  4. gita.

    gita. Guest

    rcc can cause all except-
    1.polycythemia
    2.amyloidosis
    3.cushing
    4.
    ans???/??

    ans-cushing, cant give u any reference but its a repeat Q ,slightly twisted!!
  5. Guest

    Guest Guest

    Table 1
    Paraneoplastic Syndromes in Renal Cell Carcinoma


    Hypercalcemia Amyloidosis
    Hypertension Anemia
    Polycythemia Neuromyopathies
    Nonmetastatic hepatic dysfunction Vasculopathy
    Galactorrhea Nephropathy
    Cushing’s syndrome Coagulopathy
    Alterations in glucose metabolism Prostaglandin elevation
  6. gita.

    gita. Guest

    in t/t of ALL all r done except
    a.hydration b.allopurinol c. immediate chemotherapy d.alkalinisation
  7. sandy.

    sandy. Guest

    Administration of 0.5 mg bleomycin to mice twice weekly for 4 weeks induced pulmonary fibrosis. The initial site of injury was the intima of pulmonary arteries and veins where endothelial cells became edematous and were separated from the underlying basement membrane by large blebs. These lesions occurred after 2 weeks and were associated with infiltration of perivascular spaces by lymphocytes and plasma cells. Capillary endothelial blebbing and interstitial edema were observed after 4 weeks, when multifocal necrosis of type 1 alveolar epithelial cells was accompanied by fibrinous exudation into the alveoli. The process of repair was characterized by proliferation and metaplasia of type 2 epithelial cells, fibroblastic organization of alveolar fibrin and fibrosis of the interstitium within 8 to 12 weeks. The consistent induction of changes similar to those of diffuse pulmonary fibrosis or fibrosing alveolitis in man suggests that bleomycin-induced injury may provide a suitable model for the investigation of this ill-defined group of diseases.Full text
    Regarding Qon site of action of bleomycin i got this......but i cant deduce ans from it as the options contains endothelium ,typ 1 pneumocytes,type 2 pneumocytes!
  8. docwb

    docwb Guest

    Q.Concomitant chemoradiotherapy given in A/E:
    A)T2N0M0 glottic ca
    B)stage 3 ca cervix.
    C)ca anal canal D)nasopharyngeal ca

    Ans.A)T2N0M0 glottic ca


    Concomittent chemoradiotherapy is also used in head and neck cancers.(larynx) harrison 17th pg 550.
  9. docwb

    docwb Guest

    Q- 35yrs lady P3+0 cin3 . t/t ?
    a. LEEP
    b. hysterectomy
    c. conization
    d. cryotherapy

    ans. a. LEEP
    ref. csdt and novazek
    these write in cin3 if lady > 40yrs then hysterectomy otherwise LEEP is now t/t of choice
  10. docwb

    docwb Guest

    35 yr old F posted for TL a/e r CI for operation
    1. obesity
    2. heart disease
    3. hb<8
    4. HT
  11. docwb

    docwb Guest

    Radiotherapy is treatment of choice for T1 and small T2 GLOTTIC CANCER
    Partial laryngectomy in case of large tumor
    And quest asked was chemoradiation so no chemotherapy for glottic ca thats ans of exclusion
  12. savi.

    savi. Guest

    Q: ring fracture is present around
    1.obturator foramen
    2.glenoid cavity
    3. Foramen magnum
    4.base of metacarpal bone

    Ans:1)Obturotor foramen

    Q.HIV transmission wit highest efficacy
    1Blood transfusion 2.Needle prick 3.Homosexuals 4.Heterosexuals

    ANS: 1)Blood transfusion
  13. santa.

    santa. Guest

    No it is not imaging because Harrison mentions that CT and MRI normal does not rule out TOS. In TOS neurological presentation is common 90% so what's the benefit of DSA. IT IS CLINICAL EXAMINATION>
  14. ked.

    ked. Guest

    Signs of successful Stellate block A/E
    1.Nasal stuffiness
    2.Guttman sign
    3.Horner's syndrome/Miosis
    4. Bradycardia.

    Patient with Down's syndrome posted for operative investigation advised is
    ECHO
  15. ked.

    ked. Guest

    A 9 yr old girl having bleeding with prolonged aPTT but normal PT, diagnosis,
    1. Haemophilia A
    2. Haemophilia B
    3. vonWillebrand's disease
    4. Factor V mutation

    Laparascopy is contraindicated in A/E
    1. MI
    2. Hiatus hernia
    3. Obesity
  16. docsa.

    docsa. Guest

    no dear its 35yr old confirmed 100%
    coz ithought d lady has enough life 4 sex ( not related 2 ans but i thought)
  17. drusti.

    drusti. Guest

    A 9 yr old girl having bleeding with prolonged aPTT but normal PT, diagnosis,
    1. Haemophilia A
    2. Haemophilia B
    3. vonWillebrand's disease
    4. Factor V mutation

    Laparascopy is contraindicated in A/E
    1. MI
    2. Hiatus hernia
    3. Obesity



    Ans:Vonwillbrand disdase.......

    ....Hiatus hernia
  18. karnik.

    karnik. Guest

    compiling all the answers here.........

    1.bone mineralization marker
    ans : labelled tetracycline
    2.atheletic pubalgia
    ans: abdominal muscle strain
    3.The International Prognostic Index of lymphoma(I haemoglobin and serum pr h 17th 692
    4.which of the following does not occur in rcc cushing syndrome h 17th 592
    5.prognostic indicator of colon cancer lymph node status h 17th 575
    6 mutation not found in colon cancer beta catenin h 17th 574
    7.not a part of pancreatic cancer p53 mutation found in 75%cases h 17th 587
    8 does not cause folic acid deficience chloroquine h 17th 649
    9.not a component of pnh massive splenomegally h 17th 66
    10.a q about small cell carcinoma most sensitive to chemotherapy h 17th 561
    11 which of the following does not increase appetite msh h 17th 464
    12.which of the following is not done in ca ovary staging peritoneal biopsy h 17th 605
    13 which of the followin is not a type of analytical study field trial park 19th 58
    14 not a useful component of chronic disease depends upon dose park 19th 84
    15 chemoprophylaxis is given in all except typhoid park 19th 106
    16 q fever transmission by aerosol park 19th 252
    17 1 q about not includede in aids control programme supply of ART park 17th 357
    18.average indian man 60 kg park 500
    19.incidence can be calculated by prospective cohort studypark 19th 71
    20.vit a prophylaxis is type of specific protection park 19th 39
    21.late expanding phase means birth rate falls and death rates declines still further park 19th 379
    22.aging which of the following true oxidative free radical robbins 7th 42
    23 hallmark of acute inflamation vasodilatation and increased vascular permeability r 50
    24 which of the following specifically found in intrinsic pathway factor 12 r 128
    25 not seen in idiopathic pulmonary hemosiderosis eosinopenia r 746
    26 hypersensitive pneumonitis is type of type 3 hypersensitivity r 739
    27.marker of gist cd 117 r 827
    28.lymphoid tissue found in small intestine in submucosa r 829
    29.finish type nephrotic syndrome is due to nephrin gene r [snip]
    30. xanthogranulomatous pyelonephritis false is causative organism is tb r 1001
    31.in beningn nephrosclerosis specific finding hyaline arteriosclerosis r 1006
    32.moderate increase is incidence of breast cancer by atypical hypeplasia r 1130
    33/reversible ischemia most sensitive tst thallium scan h 17th 1519
    34.not a component of SIRS thrombocytopenia h 17th 1696
    35.child with multiple renal cysts false is autosomal inheritence h 17th 1796
    36.chief cells are found in fundus of gastric gland h 17th 1855
    37 differance between follicular adenoma nd carcinoma vascular invasion h 17th 2245
    38. a patient with family history of diabetis with absent ketonuria cant be diagnosed as type 1 DM
    h 2279
    39 which of the following is tre about sertoli cell helps in spermiogenesis h 17th 2312
    40.which of the following is false about trochlear nerve supply ipsilateral superior oblique muscle h 17th 193
    41.does not cause diarhea by invasion b.cereus h 17th 248
    42.which of the following does not cause increased anion gap diarhea h 17th 290
    43.which of the following does not cause hirsutism hyperthyroidism h 17th 301
    44.most common cause of superficial v thrombosis intravenous infusion csdt 12th 858
    45.chronic ischemia causes rest pain csdt 12th 798
    46.best nonoperative treatment for stress incontinence pelvic floor exercise csdt 1072
    47.sigmoid curve in hemoglobin oxygen binding is due to cooperative binding harper 27th 43
    48.HBS causes defect in solubility harper 27th 47
    49 which of the following is false about lipoprotein lipase does not require apo c II as cofactor har 219
    50.which of the following helps in intron removel snRNA har 27th 319
    51.which of the following helps in DNA nick sealing DNA ligase har 27th 336
    52 sodium bicarbonate is added to local Anaesthesia to increase speed of onset katjung 10th 419
    52. all except 1 can be used in acute closure glaucoma clozapine ref
    53 . 1 repeat q from nov 2008 about zn causes pulmonary fibosis
    54 1 repeat q from nov 2008 as drug causin bone formation and antio resorptive strontium ranelate
    55 1 repeat q about c wave in JVP due to bulging of av valve in to right atria
    56 triple phosphete stones is due to proteus infection h 17th 1819
    57.false about treatment of chronic low back pain bed rest 4 3 month h 17th 115 its given tht bed rest should not exceed 2 days
    58.hyperaldosteronism all are true except metabolic acidosis h 17th 288
    59.which of the following causes fastest reduction in k+ level in hyperkalemia glucose with insulin
    60scarring alopecia is caused by lichen planus h 322
    61.a q was there like a female child came 4 tosillectomy with increased a PTT diagnosis isVWF disease h 723
    62.a q was there with some older aged male with lytic bone lesion rest i dont remember but the dignosis is multiple myeloma and investigation to be done is serum electrophoresis h 704
    63.p.multocida is caused by animal bite h 801
    64 all are true except necrotisin fascitis ... its caused by grp b streptococcus h 17th 801
    65.fishy odour is found in gardnella infection h 17th 827
    66.a q was thr with infection and mode of transmission with listeria legionella n tetanus as choice ans the wrong ans is tetanus is due to aerosol dust h 17th 898
    67.culture media used for etec o157 is sorbitol mc konky media h 17th 942
    68.endemic relapsing fever is caused by a/e b.recurrentis h 17th 1052
    69 a/e are true about parvo virus is transplacental fetal infection incidence is <,10% h 17th 1116
    70.HIV infects predominently CD4 h 17th 1139
    71.hiv induced cardiomyopathy all are true except it causes aortic aneurism h 1174
    72.enterovirus causes a/e hemmorhagic fever h 1209
    73.dengue hemmorhagic fever is caused by reinfection with another dengue virus serotype h 1239
    774 drug of choice in severe falciperum malaria artesunate h 1289
    75.maltese cross on immunoforoscence babesia microti h 1295
    76.true about simple random saampling each unit has a n equal chance of being drawn park 703
    77.a q about comet tail appearance adenomyosis of gall bladder repeat from nov 2008
    78.obstructive azoospermia true statement is normal fsh with normal lh h 2314 its given normal fsh only not mentioned abt lhi will search 4 further referanc
    79.a/e are true abt eaton lambert syndrome spare ocular m. H 2674
    80.signal transmission occurs between cell by all route except gap junction ganong 22nd 16
    81..which of the following is true about fascilitated diffusion does not require energy gan 31
    82.intrinsic factor is secreted by parietal cells gan 491
    83.which of the following is secreted by paneth cells lysozyme gan 506,518
    84.which of teh following is not a function of CD4 helper cell >>>>>>>> cytotoxicity gan 527
    85..increased blood flow to muscle during exercise is due to accumulation of vasodilator metabolites gan 632
    86.diastolic flow in aorta is due to elastic recoil of aortic wall gan 587
    87..primary stimulus to chemoreceptors is due to increased h+ions gan 675
    88.cyanosis does not occur in anemic hypoxia gan 684
    89.previlaged communication means relation between a dr and public authority concerned with moral dutis to protect public parikh 6th 1.34
    90.1q was thr about fingerprints are lost in leprosy repeat
    91..abrasions should be distinguished from ant bite parikh 4.3
    92.foreign body sensation in eye with arthritis diagnosis is reactive arthritis h 17th 2113
    93.which of the following is not true about angioneurotic edeme >>pittin in nature h 17th 2066...
    94.another q was there with immediately after taking some food develops dyspnea cyanosis dianosis is angioneurotic edema h 2066
    95..not a direct cutaneous disease reiters disease h 2066
    96.extensive abrasions are found on the body of a pedestrian lying by the road side. What is the cause secondary impact injury not secondary injury as it occurs on opposite side of primary impact injury parikh 4.133
    97. 20yrs. old male with Hb-10 MCV 70 serum iron 65 serum ferritin 100 what is the diagnosis.... thallasemia trait table 6 page 633 and table 99.2 page 637
    99.sleep is controlled by which centre hypothalamus h 173
    100.myoodesis is c/i in ischemia
    101.intermittent claudication pain is produced during exercise h 1168
    102. cell cycle specific agent bleomycin katzung 881
    103.ifosphamide is an alkylating agent katzung 882
    104..true about nitroglycerine except hypotension and bradycardia kat 187
    105.valproate causes a/e osteomalacia kat 387
    106..water sample estimation all are true except cl.perfringes spore denotes recent contamination park 580
    107.INMCI does not include tb park 372
    108..pseudoclaudication is due to ---- COMPRESSION OF CAUDA EQUINNA (repeat question
    109.Cap in lac operon is - positive regulator {repeat}
    110.Shortest interval in onset to death- pph dutta 6th 412
    111..a female child was brought with complaint of generalised swelling of her body. She was passing fatty cast in her urine. No haematuria. The true statement is – no IgG or C3 deposition seen on renal biopsy h 1790
    112.von hippel landau syndrome consists of a/e – gastric cancer repeat
    113.triple assessment of breast dis includes clinical ex,mammogram,aspiration h 564
    114.the following cephalosporin doesn’t need dose modifications depending on gfr values – cefoperazone kat 737
    115.tacrolimus side effect – nephrotoxicity kat 918
    116./hand foot and mouth syndrome – capecitabin kat 888
    117.the following drug can be given safe in pregnancy - propylthiouracil kat 626
    118. cystic fibrosis all are true except – defect in calcium channel h 1632
    119.girl with abnormal sweat chloride test, next diagnostic test – transnasal potential difference h 1634
    120. HepB infected neonate - both Vaccine and Immunoglobin repeat
    121.Joint aspiration in acute gout shows prdominent neutrophills h 2166
    122.About mesial temporal lobe epilepsy true is it involves hippocampus h 2500
    123.Lupus anticoagulant true is specifically increases PTT h 731
    124..Nerve entrapment all except femoral h 2654
    125.the nephrotoxicity of cisplatin is increased by a/e – rifampicin kat 774
    126.triad of tuberous sclerosis a/e rhabdomyoma h 2607
    127. Coombs positive anaemia – sle h 659
    128.normal curve mean=median b k mahajan 6th ed 81
    129.abt apla syndrome all are true except severe laife threatening hemmorhage ref i will give soon
    130.contineous data is represented by histogram mahajan 20
    131.baby clinic a/e helping mother to initiate breast feeding with in 4 hr of normal vaginal delivery park 444
    132.the following vaccine when contaminated causes toxic shock syndrome – measles vaccine park 129
    133. abt hemochromatosis true is heterozygosity h 2430
    134.Proteus –ans. triple phosphate renal stone h 1819
    135. Milkman # - pseudo#
    136.true about trroters triad except seizures repeat with different choice
    137.dense mammogram in young female is due to more glandular tissue
    138.gold standard test to diagnose insulinoma 72 hr fasting plasma glucose level
    139.pulsatile large liver is seen in tricuspid regurgitition h 1479
    140.after 4 days of fasting glucose receptors increase in all except adipose tissue harper 27th 140
    141. commonest organ to be injured in bomb blast – lung parikh 4.184
    142.thromboembolism assoc with a/e – pnh h 660
    143.vaginal delivery not allowed in twin with 1 vertx n other with non vertex presentation dutta 211
    144.all are effect of estrogen except decreased HDL kat 658
    145.smoking assoc with a/e nasopharyngeal cancer h 487
    146.all are included in nutritional surveillance except maternal haemoglobin <11.5% park 519
    147. thorasic outlet syndrome is diagnosed by DSA as clinical examination finding is similar with cervical disk disease and X RAY is not diagnostic and DSA shows post stenotic dilatation which is definitive csdt12th 822
    148.mifepristone can be given in fibroid uterus shaw 345but its also given in ectopic pregnancy any plz hlp
    149.carpal tunnel syndrome caused by a/e addisons disease h 2154
    150.a/e is a cause of priamry amennorhe a.... sneehans syndrome shaw 280
    151.all are C/I of laparoscopic sterilisation except obesity as its C/I in extreme obesity not obesity shaw 238
    152.best contraceptive in lactation progesterone pill as its male condom thts effective not female condoms so a generalised term of barrier method cant be best in lactation shaw 240 dutta 548
    153..neonate with scarred and hypoplastic limb .. congenital varicella
    154.mother in 1st trimester pregnancy with irregular use of spiramycin gave birth to a baby with hydrcephalus diagnosis is congenital toxoplasmosis h 1308
    155.a q was thr abt SDS PAGE ans is it causes protein denaturation the b choice in the q har27th24
    156.acetyl coA is a direct precurser of a/e glucose harper27th 139
    157.mi RNA helps in gene regulation harper 320
    158.angiotensin a/e – vasodilatation gan 456
    159.renal Physiology a/e –kidney bears 5 % of cardiac output is the ans gan 708
    160..Anatomical snuff box – radial a repeat
    161. Pauci immune glomerulonephritis – microangiopathic polyangitis rob 977
    162.a/e are true about neuroblastoma invove aorta and branches at early stage. opg 573
    163.bld supply of medulla are a/e basilar a bdc 304
    164. trauma patient with gcs score 15, bp 100/80 next step iv fluid with blood for cross matching csdt 214
    165.content of deep perineal pouch a/e root of penis repeat
    166.part of pelvic diaphragm a/e - colles fascia bdc 332
    167. posterior superior alveolar artery is a branch of – palatine br of maxiilary bdc 120
    168.a lady with temporal field defects, galactorrhoea, most common cause – pituitary macroadenoma h 2202
    169.orphan annie nuclei is found in a/e follicular carcinoma thyroid h 2245
    170.hepatomegaly is caused by all except hepatic pophyria plz look the porphyria chapter frm harrison 2438
    171.lithium can be used in all except generalised anxiety disorder as its also used in cluster headache but no where mentioned in generalised anxiety disorder in hari 2712 abt lithium so the ans wd be generalised anxiety disorder
    172.dysgerminoma marker – LDH
    173.superior gluteal nerve supplies all except – gluteus maximus
    174.45 year old male had a chest pain. he died after 4 days. on postmortem intramural coagulation was found. true finding is presence of granulomatous inflammation r 579
    175.spstic paraplegia is caused by all except lead poisoning
    177. evidence based treatment fr mennorrhagia are a/e ethamsylate 178.secretomotor fire to parotid pass through a/e greater petrosal n bdc 127
    179.the most bactericidal among the following oxygen free radical r 61,75
  19. mpsinha.

    mpsinha. Guest

    Box 2 : Efficacy of routinely used vaccines*
    Diphtheria: 87%-96%
    Tetanus: >90%
    Pertussis: 35%-96%
    Recent studies have shown that pertussis vaccines currently in use in the United Kingdom have efficacies of over 90%
    Haemophilus influenzae type b (conjugate vaccines): 94%-100%
    The polyribosylribitol phosphate-diphtheria toxoid conjugate vaccine (not used in the United Kingdom or the United States) may have a lower efficacy in some populations
    Oral polio: 90%-100%
    Oral polio vaccine seems to be less immunogenic in developing countries
    Measles: 90%-95%
    Mumps: 90%-98%
    The Rubini strain of vaccine virus has a lower efficacyin fact, a general study showed it to have no protective efficacy14
    Rubella: >95%
    BCG (Bacille Calmette-Guérin): 0%-80%
  20. mpsinha.

    mpsinha. Guest

    Lithium Carbonate Has No Measurable Effect on Cerebral Hemodynamics in Cluster Headaches

    Manuscript submitted for the 1983 Harold G. Wolff Award.


    *Franzheim Synergy Trust International Research fellow 1982.

    This work was supported by the Veteran's Administration, Washington, D.C. and grants from the National Migraine Foundation 1982 and US Public Health Service grant NS09287.


    ABSTRACT
    SYNOPSIS

    Any effects of lithium carbonate (oral dosage 900 mg/day) on measurements of cerebral hemodynamics were examined in 10 carefully selected patients meeting criteria of chronic cluster headache, i.e., headache-free intervals were less than 3 weeks in duration per year. Cerebral blood flow (CBF) was measured by the 133Xe inhalation method before and 2-4 weeks after (mean 3 weeks) standard recommended lithium carbonate administration, as a dose of 300 mgs give orally three times per day (total 900 mg/24 hours).Cerebral vasoconstrictor responsiveness was tested by repeated CBF measurements during serial inhalations of 100% O2 followed by 5% CO2 in air mixtures. Mean values for hemispheric gray matter flow were 70.9 ml/100g brain/min measured over the side of the cluster headaches and 70.0 ml over the contralateral side prior to lithium and 68.0 ml for sides of the head after lithium treatment. These differences before and after treatment were not significant. Cerebral vasodilator responsiveness to 5% CO2 was expressed as per cent gray matter flow change per mmHg change of measured PECO2 . Compared to values measured in normal age-matched controls, CO2 responsiveness was diminished bilaterally, both prior to and during lithium administration and there were no significant changes induced after treatment with the drug. Likewise cerebral vasoconstrictor responses during 100% oxygen inhalation were not altered by lithium treatment.
  21. mpsinha.

    mpsinha. Guest

    stellate block
    a.horner
    b.guttman's sign(nothing bt nasal stuffiness)
    c.nasal u/t stuffiness (rpt)
    d.tachycardia

    ans :d .tachycardia....(symp supply of heart is t4,t5)
  22. mpsinha.

    mpsinha. Guest

    The cytostatic drug bleomycin (BLM) induces pulmonary fibrosis as its main side effect. Fibroblasts in fibrotic foci are the main cellular source for extracellular matrix accumulation that typifies fibrosis. In vitro studies demonstrated the ability of cytotoxic drugs to induce terminal differentiation of fibroblasts. These postmitotic cells are very active in regard to production of collagens. The present study was addressed to investigate the potential of BLM to induce terminal differentiation of rat lung fibroblasts in vitro and the consequences for collagen production and for the expression and activity of the collagen modifying enzyme prolyl 4-hydroxylase (P4H). The BLM effects were compared with those of mitomycin C (MMC), another cytotoxic agent with known potential for initiation of postmitotic differentiation of fibrobasts.

    BLM induced postmitotic differentiation of rat lung fibroblasts. The capacity of the cells to form clones was diminished by BLM or MMC in a concentration dependent manner. Both drugs initiated the formation of an increasing number of postmitotic cell clones. The postmitotic differentiation was accompanied by an increase in total collagen production by the cells. Administration of BLM to cultures of lung fibroblasts at concentrations of 1 or 10 mU/ml resulted in an increase of the collagen amount to about the 1.5-fold and 1.6-fold of controls, respectively. Treatment of fibroblasts with MMC elevated the collagen level to about the 2-fold. P4H activity and P4Hα mRNA levels in cells exposed to BLM or MMC were found to be increased.

    We conclude that terminally differentiated fibroblasts might be part of the heterogeneous population of fibroblast-like cells in fibrotic foci responsible for the increased production of collagen during the fibrotic phase of the development of pulmonary fibrosis.

    Key words: Bleomycin; terminal differentiation; collagen; prolyl 4-hydroxylase; lung fibrosis
  23. mpsinha.

    mpsinha. Guest

    The effect of initial management of hyperleukocytosis on early complications and outcome of children with acute lymphoblastic leukemia
    HS Maurer, PG Steinherz, PS Gaynon, JZ Finklestein, HN Sather, GH Reaman, WA Bleyer and GD Hammond
    University of Illinois, Chicago.

    Data were collected from 124 patients with newly diagnosed acute lymphoblastic leukemia (ALL) and WBC greater than 200,000/microL seen at institutions affiliated with the Children's Cancer Study Group (CCSG) from April 1981 to May 1983. The presenting characteristics, initial management, early complications, and outcome were reviewed. All the children received vigorous intravenous (IV) hydration, alkalinization of the urine, and allopurinol. Thirty-two patients were started on full therapy with no additional measure. One or more special measures believed to reduce the complications of leukostasis and blast cell lysis were administered to 92 patients as follows: small initial doses of prednisone, 63; emergency cranial irradiation, 26; exchange transfusion, 21; and leukopheresis, 19. The incidence of CNS hemorrhage was only 3% (4/124). Seven patients expired during induction and four failed to achieve a remission by day 28. Nineteen patients (15%) had documented bacterial or fungal sepsis. Mild to moderate electrolyte abnormalities occurred in 29 patients: three patients required renal dialysis. Pretreatment with small doses of prednisone did not decrease the incidence of electrolyte abnormalities in those patients when compared with patients who received full chemotherapy. The event-free survival (EFS) for the 106 patients treated on one of the three intensive pilot studies is 55% at 36 months. On multivariate analysis the two significant adverse prognostic factors were massive splenomegaly (P = .02) and WBC count greater than 600,000/microL (P = .05). In conclusion, in patients with hyperleukocytosis the complications of blast cell lysis and leukostasis were manageable with acceptable morbidity and minimal mortality in a group of patients treated with vigorous hydration, allopurinol, and alkalinization of the urine before beginning chemotherapy. Selected patients with severe hyperuricemia and renal dysfunction may benefit from leukopheresis. No beneficial role was demonstrated for the use of small initial doses of prednisone or emergency cranial irradiation.


    So alkalinisation is done when complication occurs not routinely
  24. mpsinha.

    mpsinha. Guest

    Standard prophylaxis and treatment of malignancy-associated "hyperuricemia" in the USA has been allopurinol with vigorous hydration, urinary alkalinization and osmotic diuresis.
  25. mpsinha.

    mpsinha. Guest

    Treatment

    Remission Induction

    Intensification (Consolidation) Therapy

    Allogeneic Hematopoietic Stem-Cell Transplantation

    Continuation Treatment

    Treatment Directed to the Central Nervous System
  26. Guest

    Guest Guest

    Signs of successful Stellate block A/E
    1.Nasal stuffiness
    2.Guttman sign
    3.Horner's syndrome/Miosis
    4. Bradycardia.

    Patient with Down's syndrome posted for operative investigation advised is
    ECHO

    Signs of successful Stellate block A/E ans;bradycardia
  27. dishant.

    dishant. Guest

    which of the following reduces bone resorption as
    well as stimulates bone formation
    a. calcitonin
    b. teriparatide
    c. ibadronate
    d. strontium

    ans;d)strontium

    ref-ref-Harisson 17th edn,pg no 2407
  28. dishant.

    dishant. Guest

    Q.True about nutrition include the following except ?
    A) Vitamin A deficiency does not occur for a year or so after stopping its intake
    B) Zinc deficiency - Pulmonary fibrosis
    C) Selenium deficiency - Cardiomyopathy
    D) High Calcium in diet reduces iron absorption



    Q.Focal diffuse gall bladder wall thickening with comet tail reverberation artifacts on USG is in ?
    A) Adenomyomatosis of gall bladder
    B) Ca gall bladder
    C) Adenomatous polyps
    D) Xantho granuloma

    Answer: A) Adenomyomatosis of gall bladder


    Q.Systolic thrill is heard in Ist and 2nd Intercostal space in all except ?
    A) Pink tetralogy of fallot
    B) Ebstein's anomaly
    C) Pulmonary stenosis
    D) VSD


    Answer: A) Pink tetralogy of fallot



    Q.Indian reference man ?
    A) 55 Kg
    B) 60 Kg
    C) 65 Kg
    D) 70 Kg

    Answer: B) 60 Kg


    Q.A 29 year old male was taking oral hypoglycemic drgs and he never had ketonuria in his life . his grandfather had diabetes and his father who is only son of his grandfather did not have the disease. the type of DM the person can never have is ?
    A) Pancreatic DM
    B) MODY
    C) Type I DM
    D) Type II DM

    answer;c)Type 1 DM


    Q When the variables follow standard distribution ?
    A) mean = median
    B) median = variance
    C) mean = 2 median
    D) standard deviation = 2 variance


    Answer: A) mean = median

    Q.Mode of transmission of Q fever ?
    A) Ticks
    B) Mites
    C) Aerosols
    D) Mosquito


    Answer: A) Ticks
  29. vikas.

    vikas. Guest

    Regarding neuroblastoma-it was all are true except?

    1.It is the second most common solid malignancy of childhood after brain tumors.

    2.Neuroblastomas mets commonly to the lung.

    3.invades the aorta EARLY in the course of the disease.

    not sure abt hte 4th option.

    ans-3.
    ref robbins.

    neuroblastomas may metastasize widely through the hematogenous and lymphatic systems, particularly to liver, lungs, and bones, in addition to the bone marrow.

    Some neuroblastomas are often sharply demarcated with a fibrous pseudo-capsule, but others are far more infiltrative and invade surrounding structures, including the kidneys, renal vein, and vena cava, and envelop the aorta.


    Table 7-13. Staging of Neuroblastomas

    Stage 1 Localized tumor with complete gross excision, with or without microscopic residual disease; representative ipsilateral nonadherent lymph nodes negative for tumor (nodes adherent to the primary tumor may be positive for tumor).


    Stage 2A Localized tumor with incomplete gross resection; representative ipsilateral nonadherent lymph nodes negative for tumor microscopically.

    Stage 2B Localized tumor with or without complete gross excision, ipsilateral nonadherent lymph nodes positive for tumor; enlarged contralateral lymph nodes, which are negative for tumor microscopically.

    Stage 3 Unresectable unilateral tumor infiltrating across the midline with or without regional lymph node involvement; or localized unilateral tumor with contralateral regional lymph node involvement.

    Stage 4 Any primary tumor with dissemination to distant lymph nodes, bone, bone marrow, liver, skin, and/or other organs (except as defined for stage 4S).

    Stage 4S* Localized primary tumor (as defined for stages 1, 2A, or 2B) with dissemination limited to skin, liver, and/or bone marrow (<10% of nucleated cells are constituted by neoplastic cells; >10% involvement of bone marrow is considered as stage 4); stage 4S limited to infants <1yr.
  30. sindhu.

    sindhu. Guest

    Q. True about nutrition include the following except?

    A) Vitamin A deficiency does not occur for a year or so after stopping its intake
    B) Zinc deficiency - Pulmonary fibrosis
    C) Selenium deficiency - Cardiomyopathy
    D) High Calcium in diet reduces iron absorption

    Q. Focal diffuse gall bladder wall thickening with comet tail reverberation artifacts on USG is in?

    A) Adenomyomatosis of gall bladder
    B) Ca gall bladder
    C) Adenomatous polyps
    D) Xantho granuloma
    Answer: A) Adenomyomatosis of gall bladder

    Q. Systolic thrill is heard in Ist and 2nd Intercostal space in all except?

    A) Pink tetralogy of fallot
    B) Ebstein's anomaly
    C) Pulmonary stenosis
    D) VSD
    Answer: A) Pink tetralogy of fallot

    Q. Indian reference man?

    A) 55 Kg
    B) 60 Kg
    C) 65 Kg
    D) 70 Kg
    Answer: B) 60 Kg

    Q. A 29 year old male was taking oral hypoglycemic drgs and he never had ketonuria in his life . his grandfather had diabetes and his father who is only son of his grandfather did not have the disease. the type of DM the person can never have is?

    A) Pancreatic DM
    B) MODY
    C) Type I DM
    D) Type II DM
    Answer: c)Type 1 DM

    Q. When the variables follow standard distribution?

    A) mean = median
    B) median = variance
    C) mean = 2 median
    D) standard deviation = 2 variance
    Answer: A) mean = median

    Q. Mode of transmission of Q fever?

    A) Ticks
    B) Mites
    C) Aerosols
    D) Mosquito
    Answer: A) Ticks
  31. linezolid

    linezolid Guest

    pulmonary toxicity of bleomycin

    primary lesion--->endothelial swelling-interstitial oedema-thickened alveolar wall-reactive proliferation of type2 pneumocyte-overproduction of surfactant-disturbed monomolecular spreading of surfactant over alveolar surface-giant lamellar bodies in type 2 pneumocyte-necrosis-free surfactant phagocytized by alv macrophages- they die releasing fibroblast stimulating mediators....so primary toxicity is actually to the endothelial cell.
  32. kamal.

    kamal. Guest

    258 questions with authentic answers

    1.bone mineralization marker
    ans : labelled tetracycline
    2.atheletic pubalgia
    ans: abdominal muscle strain
    3.The International Prognostic Index of lymphoma(I haemoglobin and serum pr h 17th 692
    4.which of the following does not occur in rcc cushing syndrome h 17th 592
    5.prognostic indicator of colon cancer lymph node status h 17th 575
    6 mutation not found in colon cancer beta catenin h 17th 574
    7. not a part of pancreatic cancer p53 mutation found in 75%cases h 17th 587
    8 does not cause folic acid deficience chloroquine h 17th 649
    9. not a component of pnh massive splenomegally h 17th 661
    10. a q about small cell carcinoma most sensitive to chemotherapy h 17th 561
    11 which of the following does not increase appetite msh h 17th 464
    12.which of the following is not done in ca ovary staging peritoneal biopsy h 17th 605
    13 which of the followin is not a type of analytical study field trial park 19th 58
    14 not a useful component of chronic disease depends upon dose park 19th 84
    15 chemoprophylaxis is given in all except typhoid park 19th 106
    16 q fever transmission by aerosol park 19th 252
    17 1 q about not includede in aids control programme supply of ART park 17th 357
    18.average indian man 60 kg park 500
    19.incidence can be calculated by prospective cohort studypark 19th 71
    20.vit a prophylaxis is type of specific protection park 19th 39
    21. late expanding phase means birth rate falls and death rates declines still further park 19th 379
    22. aging which of the following true oxidative free radical robbins 7th 42
    23 hallmark of acute inflamation vasodilatation and increased vascular permeability r 50
    24 which of the following specifically found in intrinsic pathway factor 12 r 128
    25 not seen in idiopathic pulmonary hemosiderosis eosinopenia r 746
    26 hypersensitive pneumonitis is type of delayed type of hsn rctn r 739
    27.marker of gist cd 117 r 827
    28.lymphoid tissue found in small intestine in lamina p r 829
    29.finish type nephrotic syndrome is due to nephrin gene r [snip]
    30. xanthogranulomatous pyelonephritis false is causative organism is tb r 1001
    31.in beningn nephrosclerosis specific finding hyaline arteriosclerosis r 1006
    32. moderate increase is incidence of breast cancer by atypical hypeplasia r 1130
    33/reversible ischemia most sensitive tst thallium scan h 17th 1519
    34.not a component of SIRS thrombocytopenia h 17th 1696
    35. child with multiple renal cysts false is autosomal inheritence h 17th 1796
    36.chief cells are found in fundus of gastric gland h 17th 1855
    37 differance between follicular adenoma nd carcinoma vascular invasion h 17th 2245
    38. a patient with family history of diabetis with absent ketonuria cant be diagnosed as type 1 DM h 2279
    39 which of the following is tre about sertoli cell helps in spermiogenesis h 17th 2312
    40.which of the following is false about trochlear nerve supply ipsilateral superior oblique muscle h 17th 193
    41.does not cause diarhea by invasion b.cereus h 17th 248
    42. which of the following does not cause increased anion gap diarhea h 17th 290
    43.which of the following does not cause hirsutism hyperthyroidism h 17th 301
    44.most common cause of superficial v thrombosis intravenous infusion csdt 12th 858
    45.chronic ischemia causes rest pain csdt 12th 798
    46.best nonoperative treatment for stress incontinence pelvic floor exercise csdt 1072
    47.sigmoid curve in hemoglobin oxygen binding is due to cooperative binding harper 27th 43
    48.HBS causes defect in function harper 27th 47
    49 which of the following is false about lipoprotein lipase does not require apo c II as cofactor har 219
    50.which of the following helps in intron removel snRNA har 27th 319
    51.which of the following helps in DNA nick sealing DNA ligase har 27th 336
    52 sodium bicarbonate is added to local Anaesthesia to increase speed of onset katjung 10th 419
    53. all except 1 can be used in acute closure glaucoma duoxetine ref
    53 . 1 repeat q from nov 2008 about zn causes pulmonary fibosis
    54 1 repeat q from nov 2008 as drug causin bone formation and antio resorptive strontium ranelate
    55 1 repeat q about c wave in JVP due to bulging of av valve in to right atria
    56 triple phosphete stones is due to proteus infection h 17th 1819
    57.false about treatment of chronic low back pain bed rest 4 3 month h 17th 115 its given tht bed rest should not exceed 2 days
    58. hyperaldosteronism all are true except metabolic acidosis h 17th 288
    59.which of the following causes fastest reduction in k+ level in hyperkalemia glucose with insulin
    60scarring alopecia is caused by lichen planus h 322
    61. a q was there like a female child came 4 tosillectomy with increased a PTT diagnosis isVWF disease h 723
    62. a q was there with some older aged male with lytic bone lesion rest i dont remember but the dignosis is multiple myeloma and investigation to be done is serum electrophoresis h 704
    63.p.multocida is caused by animal bite h 801
    64 all are true except necrotisin fascitis ... its caused by grp b streptococcus h 17th 801
    65. fishy odour is found in gardnella infection h 17th 827
    66. a q was thr with infection and mode of transmission with listeria legionella n tetanus as choice ans the wrong ans is tetanus is due to aerosol dust h 17th 898
    67. culture media used for etec o157 is sorbitol mc konky media h 17th 942
    68. endemic relapsing fever is caused by a/e b.recurrentis h 17th 1052
    69 a/e are true about parvo virus is transplacental fetal infection incidence is <,10% h 17th 1116
    70. HIV infects predominently CD4 h 17th 1139
    71.hiv induced cardiomyopathy all are true except it causes aortic aneurism h 1174
    72.enterovirus causes a/e hemmorhagic fever h 1209
    73.dengue hemmorhagic fever is caused by reinfection with another dengue virus serotype h 1239
    74 drug of choice in severe falciperum malaria artesunate h 1289
    75. maltese cross on immunoforoscence babesia microti h 1295
    76. true about simple random saampling each unit has a n equal chance of being drawn park 703
    77.a q about comet tail appearance adenomyosis of gall bladder repeat from nov 2008
    76. obstructive azoospermia true statement is normal fsh with normal lh h 2314 its given normal fsh only not mentioned abt lhi will search 4 further referanc
    77. a/e are true abt eaton lambert syndrome spare ocular m. h 2674
    80.signal transmission occurs between cell by all route except gap junction ganong 22nd 16
    81.which of the following is true about fascilitated diffusion carrier protein mediated gan 31
    82.intrinsic factor is secreted by parietal cells gan 491
    83. which of the following is secreted by paneth cells lysozyme gan 506,518
    84.which of teh following is not a function of CD4 helper cell >>>>>>>> cytotoxicity gan 527
    85.increased blood flow to muscle during exercise is due to accumulation of vasodilator metabolites gan 632
    86.diastolic flow in aorta is due to elastic recoil of aortic wall gan 587
    87.primary stimulus to chemoreceptors is due to increased h+ions gan 675
    88.cyanosis does not occur in anemic hypoxia gan 684
    89 previlaged communication means relation between a dr and public authority concerned with moral dutis to protect public parikh 6th 1.34
    90.1q was thr about fingerprints are lost in leprosy repea
    91.abrasions should be distinguished from ant bite parikh 4.3
    92.foreign body sensation in eye with arthritis diagnosis is reactive arthritis h 17th 2113
    93.which of the following is not true about angioneurotic edeme >>pittin in nature h 17th 2066
    94 another q was there with immediately after taking some food develops dyspnea cyanosis dianosis is angioneurotic edema h 2066
    95.not a direct cutaneous disease reiters disease h 2066
    96.extensive abrasions are found on the body of a pedestrian lying by the road side. What is the cause secondary impact injury not secondary injury as it occurs on opposite side of primary impact injury parikh 4.133
    97. 20yrs. old male with Hb-10 MCV 70 serum iron 65 serum ferritin 100 what is the diagnosis thallasemia trait table [snip]-6 page 633 and table 99.2 page 637
    [snip].Which of these is an FDA approved indication for use of modafinil as an adjunct obstructiv sleep apnoea h 178
    99. sleep is controlled by which centre hypothalamus h 173
    100.myoodesis is c/i in ischemia
    101 intermittent claudication pain is produced during exercise h 1168
    102 cell cycle specific agent a/e vinblastine bleomycin katzung 881
    103ifosphamide is an alkylating agent katzung 882
    104.true about nitroglycerine except hypotension and bradycardia kat 187
    105. valproate causes a/e osteomalacia kat 387
    106.water sample estimation all are true except cl.perfringes spore denotes recent contamination park 580
    107 INMCI does not include tb park 372
    108.pseudoclaudication is due to ---- COMPRESSION OF CAUDA EQUINNA (repeat question)
    109.Cap in lac operon is - positive regulator {repeat}
    110.Shortest interval in onset to death- pph dutta 6th 412
    111.a female child was brought with complaint of generalised swelling of her body. She was passing fatty cast in her urine. No haematuria. The true statement is – no IgG or C3 deposition seen on renal biopsy
    h 1790
    112.von hippel landau syndrome consists of a/e – gastric cancer repeat
    113.triple assessment of breast dis includes clinical ex,mammogram,aspiration h 564
    114.the following cephalosporin doesn’t need dose modifications depending on gfr values – cefoperazone kat 737
    115.tacrolimus side effect – nephrotoxicity kat 918
    116/hand foot and mouth syndrome – capecitabin kat 888
    117the nephrotoxicity of cisplatin is increased by a/e – rifampicin kat 774
    118 the following drug can be given safe in pregnancy - propylthiouracil kat 626
    119. cystic fibrosis all are true except – defect in calcium channel h 1632
    120 girl with abnormal sweat chloride test, next diagnostic test – transnasal potential difference h 1634
    121 HepB infected neonate - both Vaccine and Immunoglobin repeat
    122 Joint aspiration in acute gout shows prdominent neutrophills or birefringent needle-shaped msu crystal h 2166
    123 About mesial temporal lobe epilepsy true is it involves hippocampus h 2500
    124 Lupus anticoagulant true is specifically increases PTT h 731
    125.Nerve entrapment all except femoral h 2654
    126.triad of tuberous sclerosis a/e rhabdomyoma h 2607
    127 Coombs positive anaemia – sle h 659
    128 normal curve mean=median b k mahajan 6th ed 81
    129. abt apla syndrome all are true except severe laife threatening hemmorhage ref i will give soon
    130.contineous data is represented by histogram mahajan 20
    131. baby clinic a/e helping mother to initiate breast feeding with in 4 hr of normal vaginal delivery park 444
    132. the following vaccine when contaminated causes toxic shock syndrome – measles vaccine park 129
    133 abt hemochromatosis true is heterozygosity h 2430
    134. Proteus –ans. triple phosphate renal stone h 1819
    135. Milkman # - pseudo#
    136.dense mammogram in young female is due to more glandular tissue
    137 gold standard test to diagnose insulinoma 72 hr fasting plasma glucose level ref
    138.true about trroters triad except seizures repeat with different choice
    139. pulsatile large liver is seen in tricuspid regurgitition h 1479
    140 after 4 days of fasting glucose receptors increase in all except adipose tissue harper 27th 140
    141 commonest organ to be injured in bomb blast – lung parikh 4.184
    142 thromboembolism assoc with a/e – diabetes h 660
    143.vaginal delivery not allowed in twin with 1 vertx n other with non vertex presentation dutta 211
    144. all are effect of estrogen except decreased HDL kat 658
    145.smoking assoc with a/e nasopharyngeal cancer h 487
    147 all are included in nutritional surveillance except maternal haemoglobin <11.5% park
    519
    148 thorasic outlet syndrome is diagnosed by DSA as clinical examination finding is similar with cervical disk disease and X RAY is not diagnostic and DSA shows post stenotic dilatation which is definitive csdt12th 822
    149.mifepristone can be given in fibroid uterus shaw 345
    150. carpal tunnel syndrome caused by a/e addisons disease h 2154
    151 a/e is a cause of priamry amennorhe a.... sneehans syndrome shaw 280
    152 all are C/I of laparoscopic sterilisation except obesity as its C/I in extreme obesity not obesity shaw 238
    153 best contraceptive in lactation progesterone pill as its male condom thts effective not female condoms so a generalised term of barrier method cant be best in lactation shaw 240 dutta 548
    54.neonate with scarred and hypoplastic limb .. congenital varicella
    155 mother in 1st trimester pregnancy with irregular use of spiramycin gave birth to a baby with hydrcephalus diagnosis is congenital toxoplasmosis h 1308
    156 a q was thr abt SDS PAGE ans is it causes protein denaturation the b choice in the q har27th24
    157 acetyl coA is a direct precurser of a/e glucose harper27th 139
    158 mi RNA helps in gene regulation harper 320
    159. angiotensin a/e – vasodilatation gan 456
    160. renal Physiology true – 5%of cardiac output received by kidney gan 708
    161.Anatomical snuff box – radial a repeat
    162 Pauci immune glomerulonephritis – microangiopathic polyangitis rob 977
    163 a/e are true about neuroblastoma mst common mets to lung
    164 bld supply of medulla are a/e basilar a bdc 304
    165. trauma patient with gcs score 15, bp 100/80 next step iv fluid with blood for cross matching csdt 214
    166 content of deep perineal pouch a/e root of penis repeat
    167.part of pelvic diaphragm a/e - colles fascia bdc 332
    168. posterior superior alveolar n is a branch of – ifraorbital nerve
    69 a lady with temporal field defects, galactorrhoea, most common cause – pituitary macroadenoma h 2202
    170 orphan annie nuclei is found in a/e follicular carcinoma thyroid h 2245
    171 hepatomegaly is caused by all except hepatic pophyria plz look the porphyria chapter frm harrison 2438
    172 lithium can be used in all except generalised anxiety disorder as its also used in cluster headache but no where mentioned in generalised anxiety disorder in hari 2712 abt lithium so the ans wd be generalised anxiety disorder
    about
    173. dysgerminoma marker – LDH
    174.superior gluteal nerve supplies all except – gluteus maximus
    175.45 year old male had a chest pain. he died after 4 days. on postmortem intramural coagulation was found. true finding is presence of granulomatous inflammation r 579
    176 spstic paraplegia is caused by all except lead poisoning
    176 evidence based treatment fr mennorrhagia are a/e ethamsylate
    177,secretomotor fire to parotid pass through a/e greater petrosal n bdc 127
    178 the most bactericidal among the following oxygen free radical r 61,75
    179.spongy urethra drainage into which node – deep inguinal
    bdc 350
    180.chemoradiation is given in a/e glottic T2 cancr ref dhingra and plz review h 608 4 trt in cancer cx its given in it
    181.angiogenesis requires a/e –can any 1 tell me whts the choice in ths q IL8 or IL 1 as i remember i had marked it thnkn it IL!
    182.peripheral pulmonary a. prunning is seen in pulmonary hypertension h 1576
    183.paneth cell secret lysozyme
    184 best predictor of CHD lipoprotein a park 306
    185 not a feature of right heart failure increased PCWP r 563
    186 not afeature of hasimotos thyroiditis orphan an nuclei h 2230
    187 not a feature of temporal arteritis worsens on warmth exposure h 96
    188 LDH level raised in retinoblastoma khurana 4th 282
    189 motorcyclist's fructure means base of skull divided into 2 halves reddy synopsis 19th ed 129
    190 traumatic asphyxia seen in a/e accidental strangulation reddy 163
    191 casper dictu denotes time since dath reddy 85
    192 pain sensitive structures a/e choroid plexus repeat
    193 all are indicated in treatment of proliferative diabetic retinopathy except exphotocoagulation parson 20th 297
    194 all are seen in idiopathic juvenile arthritis except rheumatoid nodule
    195 stellate wound contact shot injury reddy 111
    196.35 yr female para 3+0,CIN 3 in one quadrant on pap smear, what is the management cone excision as it provides tissue for biopsy also shaw 385 h 608
    197 45 yr man with 2 cm papillary ca thyroid nodule on left lobe trt of choice is near total thyroidectomy with lt RND csdt 285
    198.amifostine is protective in all except cns
    199.karyotyping used for – chromosomal abnormalities
    200 regarding topical mitomycin c i want to tell that after searching so many internet sites i got the result thah it can be given in laryngeal stenosis and also struge weber syndrome rest the wish of AIIMS faculty
    201.zenker diverticulum
    202.risk factor for gb polyp turning into malignancy a/e size 5mm or >
    203.apoptosis which cell organelle responsible – mitochondria rob 29
    204 Sympathectomy usefull in all except anhydrosis repeat
    205.visual cycle – opsin combines with retinol repeat
    206 a q on genomic imprinting
    207.splenic artery br a/e right gastro epiploic
    208 stellate ganglion block causes all except – bradycardia
    209.neurofibromatosis a/e ans is autosomal recessive
    210. a q about malformation
    211. DSM IV include benefit for mental retardation
    212 most common site of subclavian a stenosis 1 st part
    213.214 Which of these is a set point which is framed for a long term plans, but yet something that can not be quantified/measured? Objective
    214.best graft material for below inguinal ligament anastomosis reverse saphenous vein
    215,Parastomal hernia MCC-end colostomy
    216.myocardiac o2 demand depends upon duration of systole
    g 575
    217, incontinenta pigmenti? 100 percent with ocular symptoms
    218.all are true except erythrogenic toxin is plasmid mediated
    219.SEPS is used 4 veins
    220.precocious puberty boy 5years with pubic hair, bp 120/90 – 11 beta hydroxylase h 2344
    221 intestinal absorption test stoll fat estimation h 1877
    222 heat rupture true is irregular margin reddy 143
    223.Rheumatoid factor will give false negative tests with – coombs test….
    223.restless leg syndrome seen in renal failure h 174
    224.hepatitis C true statement is moost common indication 4 liver transplantation h 1990
    225. amifostine protects all organs from radiation exposure except CNS or skin actuaaly all are giving cns as ans
    226.von hippel landau syndrome consists of a/e – gastric cancer, renal cell carcinoma, phaechromocytoma, cerebral and retinal haemangiomas.
    gastric cancer r 1414
    227.arteriovenous shunt true is helps in thermoregulation
    228.aedes mosquito a/e - constant biters, eggs cannot survive more than one week without water, transmit dengue ans constant biters park 625
    229.hiv maximum transmission – homosexual, heterosexual, blood transfusion, needle prick ans blood tranfusion park 289
    230.systolic thrill in left 2nd or 3rd intercostal space is seen in a/e ,,,, subpulmonic vsd, pink TOF, ebsteins anomaly ,valvular pulmonic stenosis as per referances given i got the ans that subpulmonary vsd
    231 leptospirosis all except? antibody cn b detectd in a week
    234 a/e 1 are comlication of eclampsia deep vein thrombosis dutta 234
    235 pancreatic transplant with bladder catheter – urine amylase, blood amylase, blood glucose ans urinary amylase
    236.aortic aneurysm rupture occurs mostly – anterior, posterior, lateral, intraperitoneal ans posterior
    237.the following joint has least chances for recurrent dislocation – ankle, hip, shoulder, knee ans ankle reviewed from various sites
    238 which of the following is not helpful in oxidation reduction reaction dehydroperoxidase har 96
    238.which true about vasomotor centre?? connected to cardiovagal fibres
    239.Closure of nueral tube begins at- Cervical
    240 rapid correction of hyperglycemia using insulin alone will result in –hypernatremia h 2285
    241 foamy histiocytes and intense neutrophilic infilterates in a patient presenting with fever and lymphadenopathy ....diagnosis is sweet syndrome
    242.most common change in child in response to hypoxia ans tachycardia
    244. sternberg camnal false is lies lateral to foramen rotundum ANS 4
    245.chemotherapeutic agent not used in osteosarcoma ACCRD TO T10 PROTOCOL ETOPOSIDE
    247 ALL OF THE FOLLOWIN ARE DIGESTED IN HUMAN INTESTINE EXCEPT lignin HAR 116
    247 energy source in restg state DEPENDS ON ?? lean body mass,heart rate,?,? LEAN BODY MASS HAR 486
    248 chlamydia true can be grown on culture
    249 i dnt remember the exact q bt mentioned tht child is bein ntubated n ventillated wht to do next thnk no ref required its ABC of resuscication bt a choice was thr as i remember secure airway as intubation is part of securin airway it has been excludedv transfusion and bood for cross matching
    250.crude birth rate a/e – ratio, fertility indicator, still born excluded
    ans fertility indicator park 386
    251 child bites his fingers – hgprtase def, adenosine deaminase def
    ans hgprt deficiency har 308
    252.pancreatic transplant+bladder drainage, investigation to evaluate function--- urinary amylase/ serum amylase/ bilirubin ans-- urinary amylase
    253 a patient with acute leukemia and hyperleiukocytosis which is not to be given imediatle ans chemotherapy ref h 680
    254 .which of the following is a non progressive esophageal contraction ans tertiary
    255.most common cause of death after 48 hr of THR PULMONARY EMBOLISM
    256.6 year old girl comes with dyspnea and cough... after primary treatment she was sent home.. a weak later the whole lung on right side was opacified on cxr... what's probable diagnosis FB ASPIRATION CSDT 1311
    257.Q. On a given day a hospital had 50 admissions. 20 girls, out of which 10 needed surgery and out of 30 boys which were admitted 20 needed surgeries. What is the probability of picking up a person requiring surgery? 2/6
    258.true about papilloma of larynx ans hpv 6 is more virulent
  33. Dr Giri

    Dr Giri Guest

    Targeted interventiön in HIV r a/e
    1 Behavior change
    2Treat f STD
    3 Condom promotion
    4 art therapy [ans]
    ref@park psm 19/359
  34. nirmal.

    nirmal. Guest

    Q.Cardiac manifestations of HIV A/E:
    1)Cardiomyopathy 2)aortic aneurysm 3)recurrent emboli
    4)Cardiac tamponade
    Ans:2


    Ref-Hari17th,1174


    Q.Which test s performed to detect reversible myocardial ischemia?
    1)Coronary angio.
    2)MUGA scan
    3)Thallium scan
    4)Resting ECHO

    Ans:3)Thallium scan


    ref:Harison17th page1519
  35. nirmal.

    nirmal. Guest

    all of the following drugs are used in narrow angle glaucoma except-

    1.duloxetine
    2.citalopram
    3.fluphenazine
    4.clozapine
    ans. 2.
  36. Guest

    Guest Guest

    IDEA-Indian disability evaluation assesment scale
    it has four components
    1) self care
    2) interpersonal relationship
    3) work
    4) communication&understanding
    ans 4
  37. Guest

    Guest Guest

    all of the following drugs are used in narrow angle glaucoma except-

    1.duloxetine
    2.citalopram
    3.fluphenazine
    4.clozapine
    ans. 4 source net
  38. the correct option for hiv were

    1) pulmonary oedema
    2) valvular defect
    3) aortic aneurysm
    4) cardiac temponade


    correct answer is aortic aneurysm
  39. ace.

    ace. Guest

    max vaccine efficacy question is a repeat from JIPMER 91 and deepak mishra has given measles as answer..
  40. mesh.

    mesh. Guest

    Also in triple a of pulse,amit ashish has given measles ans of same q=q no 334 from JIPMER 91.But park is inconclusive as it does not mention %efficacy of TT.Measles is 95%.Any one got more clear reference?

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