An 84 year old man complains of shortness of breath

Discussion in 'Plab 1 and 2 forum' started by Neha Gupta, May 28, 2013.

  1. Neha Gupta

    Neha Gupta Active Member

    An 84 year old man complains of shortness of breath. His chest x-ray reveals diffuse pleaural plaques. On further questioing it transpires that he was involved in the insulation work in the construction trade between 1940 and 1970. Investigation of this man\'s sputum is likely to reveal

    a) ferruginous bodies

    b) amyloid deposits

    c) Streptococcal laden macrophages

    d) Heberden\'s nodes

    e) Foamy macrophages

    f) amyloid material

    g) acid fast bacilli

    h) Aschoff bodies

    i) myelin plaques

    j) Donovan bodies
  2. Neha Gupta

    Neha Gupta Active Member

    ANSWER A

    Ferruginous bodies are iron coated asbestos particles seen in pulmonary asbestosis. Health hazards from asbestos dust have been recognized in workers exposed in shipbuilding trades, asbestos mining and milling, manufacturing of asbestos textiles and other asbestos products, insulation work in the construction and building trades, brake repair, and a variety of other trades. Asbestos bodies are a subset of ferruginous bodies, the structures formed when iron-protein deposition occurs on fibers, but, because asbestos is by far the most common core material, the ferruginous body is considered the microscopic hallmark of asbestos exposure. The presence of ferruginous bodies in sputum indicates a significant past exposure to asbestos. The beaded or segmented morphology of these iron-coated fibers is characteristic.

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