enzyme inhibited by aminophylline ?

Discussion in 'AIIMS Nov 2013' started by ahmad, May 14, 2004.

  1. ahmad

    ahmad Guest

    ..Which is the enzyme inhibit by aminophylline.?
    1.Monoamine oxide.
    2.Alcohol dehydrogen.
    3.Cytochrome p-450
    3.Phosphodiestetase.
  2. Guest

    Guest Guest

    Its phosphodiesterase. The main clinical effect of bronchodilation is thru' PDE type IV, though it inhibits all types non-specifically. Note that milrinone and inamrinone(old name is amrinone) inhibit specifically type III. And sildenafil inhibits type V. Note that cilostazol and pentoxifylline are also PDE inhibitors.

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