fetal blood sampling (part 2)

Discussion in 'MRCOG Forum' started by Guest, Jul 31, 2010.

  1. Guest

    Guest Guest

    http://en.wikipedia.org/wiki/Percutaneous_umbilical_cord_blood_sampling

    Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, is a diagnostic genetic test that examines blood from the fetal umbilical cord[1] to detect fetal abnormalities.

    PUBS is similar to amniocentesis, but instead of sampling the amniotic fluid which surrounds the fetus, PUBS examines fetal blood. An advanced imaging ultrasound determines the location for needle insertion into the placenta, and the needle is guided through the mother's abdomen and uterine wall into the fetal vein of the umbilical cord, where a fetal blood sample is removed

    Because the fetal vein is fragile early in pregnancy, PUBS is performed no earlier than 17 weeks into pregnancy.
  2. Guest

    Guest Guest

    Q: Antenatal fetal blood sampling
    F 10. Is necessary for the diagnosis of fetal beta thalassaemia (84 busy ans,uk:F) (lulu3:T) (busy module 6 P.4: Amniocentesis + PCR can also used for diagnosis thalassaemia) =
    F 11. Carries a 10-15% risk of premature rupture of the fetal membranes (84 busy ans,uk:F) (lulu3:T) =
    T 12. Is indicated in the investigation of fetal hydrops (84 busy ans) =
    F Has a fetal loss rate independent of indications
    T should be performed under continous ultrasonography guidance (saunder 36)
    F/?T should not be performed before 18-20 wks’ gestation (busyT, website: Because the fetal vein is fragile early in pregnancy, Percutaneous umbilical cord blood sampling (PUBS) is performed no earlier than 17 weeks into pregnancy) (Baker 219F: The procedure can be performed from 16-18weeks gestation)
    T may lead to fetal cord tamponade
    F is always performed throught the umbilical vein =- (cardiac and liver can also)
    T is a recognized indication in IUGR pregnancies

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