Lithium should be stopped how many days before surgery

Discussion in 'AIIMS Nov 2013' started by samuel, Dec 17, 2014.

  1. samuel

    samuel New Member

    Lithium should be stopped how many days before surgery
    a) 1
    b) 2
    c) 3
    d) 4
    Answer: 2 days

    Explanation:
    Lithium is used to treat bipolar affective
    disorders. It may potentiate the effect of
    depolarizing and competitive neuromuscular
    blocking agents. The clearance of lithium can
    be reduced and its toxicity increased by factors
    that cause negative fluid balance, negative
    sodium balance, and decreased glomerular
    filtration rate.
    Lithium should be discontinued 2-3 days
    before major surgery and resumed when renal
    function and electrolyte levels are stable.
    If serum levels are not in a toxic range, renal
    function is normal, and fluid electrolyte status
    is stable, lithium can be continued before minor
    surgery.

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