necrosis of the breast

Discussion in 'MRCS Forum' started by Lona., Feb 8, 2008.

  1. Lona.

    Lona. Guest

    Q. A woman sustains an injury to her chest after striking the steering wheel of her automobile during a collision. Which of the following statements concerning fat necrosis of the breast is true?
    a- Most patients report a history of trauma
    b- The lesion is usually nontender and diffuse
    c- It predisposes patients to the development of breast cancer
    d- It is difficult to distinguish from breast cancer
    e- Excision exacerbates the process
  2. Lona.

    Lona. Guest

    Answer: d. (Schwartz, 7/e, p 552) Injury to breast tissue may cause necrosis of mammary adipose tissue and lead to the formation of a tender, localized, firm mass. A history of trauma is often elicited from affected patients, but less apparent factors, such as prolonged pressure, may also produce fat necrosis. Half the patients in whom the diagnosis is made to not recall a history of trauma. The pathophysiology of this lesion seems to involve early development of liquefaction of mammary fat with the formation of a cystic mass. Through a process of fibrosis, this lesion evolves into a firm, sometimes calcified lump that may be difficult to distinguish from carcinoma. There is, however, no relation between fat necrosis and the subsequent development of breast cancer. Excisional biopsy is usually required for definitive diagnosis; if the diagnosis of fat necrosis is confirmed; simple excision removes and terminates the process.
  3. egyplabber

    egyplabber Guest

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