One month after undergoing an uneventful renal transplant for chronic renal failure secondary to glo

Discussion in 'USMLE Step 2 CK' started by samuel, Nov 12, 2014.

  1. samuel

    samuel New Member

    One month after undergoing an uneventful renal transplant for chronic renal failure secondary to glomerulonephritis, a 38-year-old woman is hospitalized because of increased serum urea nitrogen (BUN) and creatinine levels. Prior to transplantation, she had been receiving hemodialysis for 3 years. Current medications include cyclosporine and prednisone. Examination shows no abnormalities. Over the past 48 hours, urine output has remained stable. Both renal biopsy and a radionuclide scan confirm the diagnosis of acute rejection. Which of the following is the most effective treatment?

    A
    ) Immediate discontinuation of cyclosporine

    B
    ) Increased dosage of corticosteroids

    C
    ) Diuresis and alkalinization of the urine

    D
    ) Renal dialysis for 1–2 weeks

    E
    ) Transplant nephrectomy

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