Discussion in 'Question Zone' started by roma, May 16, 2004.
which of the following produce osteoblastic secondar.
1 ca lung
2 ca breast
3 ca ub
4 ca prostate
ca breast & prostate may produce osteoblastic sec. what's the answer? 1st see sex of pat., not mentioned so go for prostate as it's most common ca to go to bones. ref. bailey. see p. no. later
Bony lesions in CA Breast - OSTEOSCLEROTIC.
Bony lesions in CA Prostate - OSTEOBLASTIC.
Bony Lesions in most of other secondary malignancies - OSTEOLYTIC.
thanx, but i read for 1st time osteosclerotic sec's. which book. by the way b& l 23rd ed 1249-1250.
As far as I know, osteoblastic and osteosclerotic are one and the same. Only if it is osteoblastic, can sclerosis take place by new bone formation. I don't think this fact needs any ref.
1-- Harrison's p. 628-- read carefully--osteoblastic activity se sclerosis hota hai. also increase bone density.
2--outline of orthopedics 13 th ed by adams--p. 98-- sclerosis almost confined to prostate ca.
3--maheswari--p. 224--both breast & prostate produce sclerosis
4--CSDT 9th ed [old ed] --p. 1096--both breast & prostate osteoblastic.
in fact acc. to IT, braest is MC primary to go to bone-- i. e. contradicts bailey.
5-- CMDT 2003--P' 697-- mc site for mets of breast --of male & female--BONE. BUT STILL DOUBT-- ACC. TO TORONTO NOTES FOR MCC EXAM--MC IS LUNG AS WE COMMONLY BELIEVE!!!
DECIDE ANSWER URSELF NOW.
STILL I THINK THAT WHAT BAILEY & ADAMS HAV TO SAY-- ANS IS PROSTSTE.
I FAVOR VEIW EXPRESSED BY DR SUGANYAi.e.osteoblastic and osteosclerotic are one and the same. Only if it is osteoblastic, can sclerosis take place by new bone formation
source chapmans aids to radiological d/d
mc appearance of breast sec is lytic and mixed and of prostate is scleotic so anser is prostate check in chapmans my radiology book or aiims may 2004 paper by me being a radiologist i dont think there is any difference between osteoblastic and osteo\sclerotic
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