Pathognomonic sign-disease

Discussion in 'Dental PG MDS IQE MFDS ADC Exams' started by guest2011, Oct 30, 2012.

  1. guest2011

    guest2011 Moderator

    PATHOGNOMONICS


    1. Albumino-Cytologic Dissociation ? Guillain-Barre (markedly increased protein in CSF with only modest increase in cell count)
    2. Antiplatelet Antibodies - idiopathic thrombocytopenic purpura
    3. Arachnodactyly ? Marfan?s
    4. Aschoff Bodies ? rheumatic fever
    5. Auer Rods - acute promyelocytic leukemia (AML type M3)
    6. Autosplenectomy ? sickle cell anemia
    7. Babinski ? UMN lesion
    8. Basophilic Stippling of RBCs ? lead poisoning
    9. Bence Jones Protein ? multiple myeloma free light chains (either kappa or lambda)
    Waldenstrom?s macroglobinemia
    10. Birbeck Granules ----- histiocytosis X (eosinophilic granuloma)
    11. Blue Bloater ? Chronic Bronchitis
    12. Boot-Shaped Heart ? Tetralogy of Fallot
    13. Bouchard's Nodes - osteoarthritis (PIP)
    14. Boutonniere?s Deformity - rheumatoid arthritis
    15. Brown Tumor - hyperparathyroidism(2nd ry)
    16. Brushfield Spots -Down's
    17. Call-Exner Bodies - granulosa cell tumor
    18. Cardiomegaly with Apical Atrophy - Chagas Disease
    19. Chancre ? 1ry Syphilis
    20. Chancroid ? Haemophilus ducreyi
    21. Charcot Triad - multiple sclerosis (nystagmus, intention tremor, scanning speech)
    22. Charcot-Leyden Crystals ? bronchial asthma
    23. Cheyne-Stokes Breathing ? cerebral lesion
    24. Chocolate Cysts ? endometriosis
    25. Chvostek?s Sign ? Hypocalcemia facial spasm in tetany
    26. Clue Cells ? Gardnerella vaginitis
    27. Codman's Triangle-------osteosarcoma
    28. Cold Agglutinins-------Mycoplasma pneumoniae and infectious mononucleosis
    29. Condyloma Lata ? 2 ? Syphilis
    30. Cotton Wool Spots - HTN
    31. Councilman Bodies - dying hepatocytes
    32. Crescents In Bowman?s Capsule ? rapidly progressive (crescentic glomerulonephritis)
    33. Currant-Jelly Sputum ? Klebsiella
    34. Curschmann?s Spirals ? bronchial asthma
    35. Depigmentation Of Substantia Nigra ------- Parkinson’s
    36. Donovan Bodies - granuloma inguinale (STD)-------callymmamo.granulomatis
    37. Eburnation - osteoarthritis (polished, ivory-like appearance of bone)
    38. Ectopia Lentis ? Marfan?s
    39. Erythema Chronicum Migrans ------- Lyme Disease
    40. Fatty Liver ? Alcoholism
    41. Ferruginous Bodies -------- asbestosis
    42. Ghon Focus / Complex ? Tuberculosis (1 ? & 2 ? , respectively)
    43. Gower's Maneuver ----------- Duchenne's MD (use of arms to stand)
    44. Heberden's Nodes -------- Osteoarthritis (DIP)
    45. Heinz Bodies -------- G6PDH Deficiency
    46. Hemorrhagic Urticaria ------- Henoch Schonlein
    47. Heterophil Antibodies ----- infectious mononucleosis (EBV)
    48. Hirano Bodies -------- Alzheimer's
    49. Hypersegmented PMNs -------- Megaloblastic anemia
    50. Hypochromic Microcytic RBCs ? iron-deficiency anemia
    51. Jarisch-Herxheimer Reaction ? Syphilis over-aggressive treatment of an asymptomatic pt. that causes symptoms 2? to rapid lysis
    52. Joint Mice ------- osteoarthritis (fractured osteophytes)
  2. guest2011

    guest2011 Moderator

    53. Kaussmaul Breathing ? acidosis
    54. Keratin Pearls ------- SCC
    55. Keyser-Fleischer Ring ? Wilson?s
    56. Kimmelstiel-Wilson Nodules --------- Diabetic Nephropathy
    57. Koilocytes ------- HPV
    58. Koplik Spots ? measles
    59. Lewy Bodies - Parkinson's (eosinophilic inclusions in damaged substantia nigra cells)
    60. Lines of Zahn ------- arterial thrombus
    61. Lisch Nodules --------- neurofibromatosis (von Recklinhausen's disease)
    62. Lumpy-Bumpy IF Glomeruli -------- poststreptococcal glomerulonephritis
    63. McBurney?s Sign ? appendicitis (McBurney?s Point is 2/3 of the way from the umbilicus to anterior superior iliac spine)
    64. Michealis-Gutmann Bodies ------- Malakoplakia
    65. Monoclonal Antibody Spike ---------- multiple myeloma.This is called the M protein (usually IgG or IgA)
    MGUS
    66. Myxedema - hypothyroidism
    67. Negri Bodies - rabies
    68. Neuritic Plaques --------- Alzheimer's
    69. Neurofibrillary Tangles ----- Alzheimer's
    70. Non-pitting Edema - Myxedema \\\\ Anthrax Toxin
    71. Notching of Ribs ? Coarctation of Aorta
    72. Nutmeg Liver ? CHF
    73. Painless Jaundice -------- pancreatic CA (head)
    74. Pannus - rheumatoid arthritis
    75. Pautrier's Microabscesses --------- mycosis fungoides
    (cutaneous T-cell lymphoma)
    76. Philadelphia Chromosome CML/AML
    77. Pick Bodies ------- Pick's Disease (fronto-parietal atrophy)
    78. Pink Puffer ? Emphysema Centroacinar ? smoking Panacinar - a1-antitrypsin deficiency
    79. Podagra ------- gout (1st MP joint -hallux)
    80. Port-Wine Stain - Hemangioma
    81. Posterior \Anterior Drawer Sign --------- tearing of the ACL
    82. Psammoma Bodies ------Papillary adenocarcinoma of the thyroid .
    Serous papillary cystadeno ca. of ovary
    Meningioma
    Mesothelioma
    83. Pseudohypertrophy ------- Duchenne muscular dystrophy
    84. Punched-Out Bone Lesions -----multiple myeloma
    85. Rash on Palms & Soles --------- 2'Syphilis ,RMSF
    86. Red Morning Urine ----- PNH
    87. Reed-Sternberg Cells ? Hodgkin?s Disease
    88. Reid Index Increased ? chronic bronchitis
    89. Reinke Crystals ------ Leydig cell tumor
    90. Rouleaux Formation ---- multiple myeloma RBC's stacked as poker chips
    91. S3 Heart Sound ----- L2R Shunt (VSD, PDA), MR, LVF
    92. S4 Heart Sound ----- Pulmonary Stenosis , Pulmonary HTN
    93. Schwartzman Reaction-N. meningitidis impressive rash with bugs
    94. Simian Crease ------ Down?s
    95. Smith Antigen ----- SLE (also anti-dsDNA)
    96. Soap Bubble on X-Ray - giant cell tumor of bone
    97. Spike & Dome Glomeruli -MGN [snip].
    98. String Sign on X-ray --- Crohn's bowel wall thickening
    99. Target Cells ? Thalassemia
    100. Tendinous Xanthomas ----- Familial Hypercholesterolemia
    101. Thyroidization of Kidney ----- chronic pyelonephritis
    102. Tophi ? gout
    103. Tram-Track Glomeruli -----membranoproliferative glomerulonephritis (MPGN)
    104. Trousseau's Sign ------ visceral ca_ classically pancreatic (migratory thrombophlebitis)
    -- hypocalcemia (carpal spasm)
    [These are two entirely different disease processes and different signs, but they unfortunately have the same name.]
    105. Virchow's Node ---- supraclavicular node enlargement by metastatic carcinoma of the stomach
    106. Warthin-Finkeldey Giant Cells ---------- Measles
    107. WBC Casts ? pyelonephritis
    108. Wire Loop Glomeruli ---------- lupus nephropathy, type IV
    109. AFP in amniotic fluid or mother?s serum ? Spina Bifida
    ? Anencephaly
    110. Uric Acid------------Gout
    Lesch Nyhan
    Myeloproliferative Disorders
    Diuretics (Loop & Thiazides)
    111. FEV1/FVC ? COPD

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