Rapid revision

Discussion in 'DNB CET board - DipNB' started by samuel, Dec 15, 2014.

  1. samuel

    samuel New Member

    CHROMOSOME 15 :
    Albinism
    Angelman syndrome (Maternal deletion or
    Paternal Disomy)
    P rade r willi syndrome ( P aternal Deletion
    or Maternal Disomy)
    Tay Sachs disease.
    Marfan syndrome.
    Bloom syndrome.



    Point to note :
    Fibrillin gene 1 (FBN 1) - On chromosome 15 - Marfan Syndrome.
    Fibrillin gene 2 (FBN 2) - On chromosome 5 - Beals syndrome
  2. samuel

    samuel New Member

    main reasons of unconsciousness..if patient is unconscious, how to differentiate and diagnose the reason..
    1) gums are swollen and tongue bite_ epilepsy.
    2)wet on forehead and severe perspiration_ hypoglycemia.
    3)hot forehead and high fever_ cerebral malaria
    4)high fever and neck stiffness_ pyogenic meningitis
    5)fever and neck stiffness_ T.B. meningitis, sub arachnoid haemorrhage.
    6)very hot forehead_ heat stroke.
    7)eyes yellow_ jaundice( hepatic coma ).
    8)eyes red and congested_ alcoholic coma.
    9)pupils unequal_ cerebral haemorrhage.
    10)bilateral pinpoint pupils_ pontine haemorrhage.
    11)dilated pupils_ dhatura poisoning.
    12)nasolabial folds unequal_ paralysis.
    13)blood in nose and ears_ haemorrhage in base of brain
    14)blue lips_ COPD patient
    15)fruit smell_ diabetic coma.
    16)urine smell _ uremic coma.
    17)rotten rat smell_ hepatic coma.
    18)perfume smell_ sleeping pills poisoning.....
  3. samuel

    samuel New Member

    AIIMS NOV 2014: PHARMACOLOGY (Solved Paper)
    1. Apoptosis caused by
    a) Oleic acid
    b) Glucocorticoid
    c) Myristic acid
    d) Isoprenoid

    Answer: Glucocorticoid
    Explanation:
    Drugs inducing apoptosis:
    Glucocorticoid
    Anti-cancers drugs
    NSAID

    2. True about Penicillin-G
    a) Broad spectrum
    c) Given orally
    c) Used in rat bite fever
    d)

    Answer: Used in rat bite fever
    Explanation:
    Penicillin’s spectrum-
    Narrow-spectrum:
    Benzathine penicillin, Benzyl-penicillin (penicillin G), Procaine penicillin
    Moderate-spectrum:
    Amoxicillin, Ampicillin
    Broad-spectrum:
    Amoxicillin & clavulanic acid
    Extended-spectrum:
    Carboxy-penicillin
    Carbenicillin Ticarcillin
    Penicillin D is given intravenously.
    Clinical Indications:
    Rat bite fever
    Meningococcal meningitis
    Disseminated gonococcal infections
    Syphilis (congenital and neuro-syphilis)
    Listeria infections
    Actinomycosis
    Botulism
    Diphtheria

    3. Which of the following incorrect about paclitaxel?
    a) Derived from E. coli
    b) Used in breast, lung and ovary cancer
    c) Myelo-suppression and alopecia
    d) Mechanism of action: Stabilize micro-tubules

    Answer: Myelo-suppression and alopecia
    Explanation:
    Paclitaxel is a natural product with antitumor activity.
    E. coli could now be used to make paclitaxel, a widely used cancer drug originally isolated from the bark of the Pacific yew tree, Taxus Brevifolia.
    Paclitaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicine cause the de-polymerization of microtubules in vivo, paclitaxel arrests their function by having the opposite effect; it hyper-stabilizes their structure.
    Paclitaxel is used in the treatment of Kaposi's sarcoma and cancer of the lung, ovarian, and breast.
    Side effects of Paclitaxel:
    Temporary hair loss
    Jaundice
    Seizure
    HTN
    Antitumor activity has been reported with minimal myelo-suppression, with paclitaxel.

    4. Drug of choice in pseudo membranous colitis
    a) Oral vancomycin
    b) Linezolid
    c) Clindamycin
    d)

    Answer: Oral vancomycin
    Explanation:
    Pseudo-membranous colitis is an acute inflammatory disease of the colon associated with C difficile. It is most commonly caused by antibiotic therapy, which alters normal bacterial flora.
    Pseudo-membranous colitis usually presents as profuse watery or mucoid foul-smelling stool with abdominal cramping and fever.
    Vancomycin is the treatment of choice for staphylococcal entero-colitis, typhlitis, and severely ill patients with C difficile colitis.

    5. Abatacept is used in treatment of
    a) Osteoarthritis
    b) RA
    c)
    d)

    Answer: RA
    Explanation:
    The Food and Drug Administration approved abatacept for rheumatoid arthritis and for children older than 6 years who have juvenile idiopathic arthritis.
  4. samuel

    samuel New Member

    Strawberry tongue- Kawasaki disease, scarlet fever
    strawberry gingivitis : Wegeners granulomatosis
    strawberry cervix : trichomonas vaginalis
    strawberry gallbladder : cholestrolosis
    strawberry nasal mucosa : sarcoidosis
    strawberry nasal mass : rhinosporidiosis



    Finger print is permanently impaired in
    Leprosy
    Electric injury
    Radiation exposure
  5. samuel

    samuel New Member

    Snow storm appearance on USG pelvis-HYDATIDIFORM MOLE
    Snow storm Ascites-MECONIUM PERITONITIS
    Snow storm Knee-SYNOVIAL CHONDROMATOSIS
    Snowman appearance on X-ray chest-UNCORRECTED TAPVC

    D/S RNA VIRUSES
    Reo virus- URTI
    Rota virus - Mc cause of infantile diarrhoea
    SS DNA virus- Parvovirus


    semen in stains identified by
    Florence test
    Acid phosphatase test
    Creatine phosphokinase test
    Barberios test
  6. samuel

    samuel New Member

    Ghon's focus -- Initial lesion in Primary TB
    (L N involved)
    Assman's focus -- Initial lesion in secondary TB (L N not involved..)


    Hair grows at the rate of 0.4 mm per day
    Nail grows at the rate of 0.1 mm per day

    HGPRTase......
    Complete deficiency...Lesch Nehans Syndrome
    Partial deficiency......Kelley Seegmiller Syndrome
  7. samuel

    samuel New Member

    autosomal dominant and recessive
    ------------------------------------------------------------
    --------------------
    (1)AUTOSOMAL DOMINANT....
    D= Dystrophicas Myotonic.
    O= Ostogenesis Imperfecta.
    M= Marfans syndrome.
    I= Intermittent Porphyria.
    N= Noonans Symdrome.
    A= Adult Polycystic Kidney,Achondroplasia.
    N= Neurofibromatosis.
    T= Tuberous sclerosis.


    (2)AUTOSOMAL RECESSIVE :
    A= Albinism.
    B= beta thalessemia.
    C= Cystic Fibrosis.
    D= Deafness.
    E= Emphysema(alpha-1 Antitrypsin
    Deficiency).
    F= Friedrichs ataxia.
    G= Gauchers disease.
    H= Homocystinuria,Hemochromatosis
    Choroso no. Abnormalities
  8. samuel

    samuel New Member

    invasive enteritis
    --------------------------------------
    yes, she shall camp close to ICU

    yes - yersinia enterocolitica
    she - shigellea
    shall- salmonella
    camp- campylobacter
    close- clostridium difficle
    to - tuberculosis
    icu - EIEC

    Constipation causing drugs
    CONSTIPA
    C-CCB-VERAPAMIL,CALCIUM CARBONATE
    O-OPIATES
    N-gaNglion blockers
    S-SULPHATE BARIUM,CALSIUM
    T-TCA,THALIDOMIDE
    I-ION EXCHANGE RESINS
    P-PHENOTHIAZENES
    A-ALUMINIUM HYDROXIDE
  9. samuel

    samuel New Member

    "cyc"s cause psychosis
    ------------------------------------------------------------
    --------------------
    cyclosporine
    cycloserine
    psychosis is side effect of both drugs

    Drugs causing pancreatitis are:
    Mnemonic:12345
    1 -ACE inhibitors
    2 -Didanosine
    3 -Trimethoprim
    4 -Tetracycline
    5 -Pentamidine
  10. samuel

    samuel New Member

    MESODERM:
    Mesothelium (peritoneal, pleural,
    pericardial)/ Muscle (striated, smooth,
    cardiac)
    Embryologic
    Spleen/ Soft tissue/ Serous linings/ Sarcoma/
    Somite
    Osseous tissue/ Outer layer of suprarenal
    gland (cortex)/ Ovaries
    Dura/ Ducts of genitalia
    Endothelium
    Renal
    Microglia/ Mesenchyme/ Male gonad
  11. samuel

    samuel New Member

    Imagine sister mary joseph playing in SLOP
    (soft mud or slush):
    S-Stomach
    L-large bowel
    O-Ovarian
    P-Pancreatic cancer
    In above cancers Mary joseph nodule is seen.


    wernikes encephalopathy
    GOA G; global aphasia
    o; ophthalmoplegia
    A; ataxia
  12. samuel

    samuel New Member

    CycloDevelopmental - CDEFG
    Elephantiasis -Filaria
    Guineaworm
    CycloPropagative - CPM - M -malaria
    "p"ropagative - "p"lague


    hypo n hyperkalemia - ecg
    -----
    T wave is a tent containing potassium.
    when k+ increases, tent is tall --tall T waves
    when k+ decreases,tent is flat -- flat T waves
  13. samuel

    samuel New Member

    sensory tracts
    ------------------------------------------------------------
    --------------------
    imagine hugging ur wife and pinching her
    hips laterally..
    so anteriorly crude touch - anterior
    spinothalamic tract
    laterally pain (&temp) - lateral spinothalamic
    tract
    and posteriorly fine touch (&
    vibration,proprio) - posterior column


    motor supply of mandibular nerve
    ------------------------------------------------------------
    --------------------
    after eating, aunt & milo played tennis
    eating - muscles of mastication
    aunt - ant belly of digastric
    milo - myelohyoid
    tennis - tensor muscles - tensor veli palati &
    tensor tympani
  14. samuel

    samuel New Member

    Diaphragmatic hernia
    MoRgAgni hernia
    m - morgagni
    R - right
    A - anterior
    so location is right anterior

    bochdalek hernia - "boch"- back - posterior
    "lek" - lateral
    so location is posterolateral
  15. samuel

    samuel New Member

    "Dish TV" decrease in "ILD/RLD".
    Dish-DLCO
    T-TLC(total lung cap.)
    V-Vital capacity
    decreased in "ILD/RLD".

    suceptibility of nerve fibres
    -------------------
    hypoxia is BACk - hypoxia B >A >C
    we are under pressure to study ABCde... -
    pressure A>B>C

    local police and CBI - local anaesthesia C >B>A
  16. samuel

    samuel New Member

    ACUTE INTERMITTENT PORPHYRIA
    BCS-PORT
    barbiturates
    cloramphenicol
    sulphonamides
    phenylbutazone
    oc pill
    rifampicin
    thiopentone


    hepatitis causing viruse......
    Pick Her Full Dailed Call
    .picorna........................ A
    .hepadna...................... B
    .flavi................................ C
    .dependent virus.... D
    .calci................................ E
  17. samuel

    samuel New Member

    saint triad-
    A "saint" says to a girl-"Hi Divine Girl."
    Here
    saint-saint triad
    1.Hi-Hiatus hernia
    2.Divine-Diverticulosis
    3.Girl (Gal)-Gall stone.

    Culex mosquito transmitted disease-
    "Cute Bantu's JAW."
    Cute-culex transmitted disease
    Bantu's-Bancrofti fever
    J-Japanese encephalitis
    A-Arthritis (viral)
    W-West nile fever.


    parasites causing loefflers syndrome/
    parasite passes through lungs........
    PAST C VAST
    .paragonimus
    .ascaris
    .stryngloids
    .tape worm
    .clonorchis
    .visceral larva migrane
    .ancylostoma
    .schistomiasis
    .trichomoNIPA



    PARASITES CAUSING AUTOINFECTION......
    "CHEST"
    .Capillary philipensis, cryptosporodium
    .H.nana
    .E.vermicularis
    .S.stercoralis
    .T.solium




    zinc containing enzymes.....
    "GLAD SCAR"
    .Glutamate dehydrogenase
    .LDH
    Alkaline phosphatase
    .DNA,RNA polymerase,
    .Superoxide dimutase
    .Carbonic anhydrase
    .Alcohol dehydroenase
    .Retinine rlymphatics


    A-P-G-A-R:
    A - appearance (color)
    P - pulse (heart rate)
    G - grimace (reflex, irritability)
    A - activity (muscle tone)
    R - respiratory effort


    soft tissue tumors spreads through
    lymphatics "SAME CLR" (same colour)
    .Synovial cell sarcoma
    .Angiosarcoma
    .Malignant fibrous histiocytoma
    .Epithelial cell sarcoma
    .Clear cell sarcoma
    .Leiomyosarcoma
    .Rhabdomyosarcoma


    Some Anatomists Like Fcuking, Others Prefer S&M
    Sup. thyroid
    Ascending Pharyngeal
    Lingual
    Facial
    Occipital
    Posterior Auricular
    Superficial Temporal
    Maxillary


    drugs causing liver granuloma ....
    "CAPSIQum" (capsicum)
    .carbamazepin
    .allopurinol
    .phenylbutazone
    .sulphonamide
    .isoniazide
    .quinidine
  18. samuel

    samuel New Member

    Suture Removal:
    -------------------------
    Head 5-7days
    Face 3-5days
    Eyelid & eyebrow 3-5days...
    Trunk 5-7days
    Extremities 7-10days
    Surface of joint 10-14days
    Hand 7days
    Sole of foot 7-10days
  19. samuel

    samuel New Member

    A)HIV transmission is by-------
    1) whole blood
    2) packed rbc
    3) platelets
    4) leucocytes
    5) plasma

    B) No-HIV –Transmission is seen with ( processing procedure will inactivate virus in all given products) ---
    1) hyperimmune gammaglobulin
    2) hepatitis B immune globulin
    3) plasma derived hepatitis B vaccine
    4) Rh0 immune globulin
  20. samuel

    samuel New Member

    Strawberry tongue- Kawasaki disease, scarlet fever
    strawberry gingivitis : Wegeners granulomatosis
    strawberry cervix : trichomonas vaginalis
    strawberry gallbladder : cholestrolosis
    strawberry nasal mucosa : sarcoidosis
    strawberry nasal mass : rhinosporidiosis
  21. samuel

    samuel New Member

    Steeple sign-ALTB(croup)
    Thumbs sign Acute epiglottis

    ##Mnemonic for radioluscent stones
    PG LUX
    (PG me ham LUX se nahate hai)
    Parotid duct
    Gallstone
    Lysine
    Uric acid
    Xanthine
  22. samuel

    samuel New Member

    #Cold-> igM
    WARM->IgG

    # Ring sideroblast is characteristicaly seen in-MDS

    #Ca.Breast is MC in- upper inner quardant

    #Iron-duodenum
    Foic acid-jejunum
    B12-ileum


    #Gonorrhoea-epididymis...no testis
    Syphilis-Testis...no epididymis
  23. samuel

    samuel New Member

    # Broken aphasia" (Broca’s aphasia- broken speech )
    # Wordys aphasia" (Wernicke’s aphasia- wordy , but making no sense)



    RMP in
    skeletal & cardiac muscle -90 mv,
    Smooth muscle -50 mv,
    SA node -60 mv,
    Nerve finer layer -70mv
  24. samuel

    samuel New Member

    PERIPHERAL SIGNS OF AORTIC REGURGITATION
    *Water- Hammer pulse
    *de Musset's sign- head nodding with each pulse
    *Quincke's sign- capillary pulsation in nail beds
    *Duroziez's sign-systoli murmer on compressing femoral artery proximally and diastolic murmer on compressing
    femoral artery distally
    *corrigan's sign-dancing carotids
    *Locomotor brachii
    *Landolfi's sign-change in pupillary size in accordance with cardiac cycle and not related to light
    *Becker's sign-retinal artery pulsations
    *Muller's sign-systolic pulsations of uvula
    *Rosenbach's sign-pulsations over the liver
    *Gerhardt's sign-pulsations over enlarged spleen
    *bisferiens pulse
    *Hill's sign-popliteal cuff systolic pressure exceeds brachial cuff pressure by >20 mmHg
  25. samuel

    samuel New Member

    1.Delirium is d/t deficiency of- Acetyl choline
    2.DOC for Adult A.D.H.D- Methylphenidate
    3.Rapid Cyclers have alternate depression episodes - 4 episodes /year



    1.% of fetal hemoglobin at birth - 70%
    2.MCHAT. is used as screening tool for - Autism
    3.In new borns, T wave elevation is seen normally upto -7 days
  26. samuel

    samuel New Member

    1.Omovertebral bone associated with - Springel s deformity
    2.Fair bank triangle related to -Coxa Vara
    3.Salter Harris classification for - Epiphyseal injuries




    1.Non Hodgkin's staging.. Adult-ANN ARBOR Child-
    SAINT JUDE
    2.MCC of sporadic viral encephalitis- HSV
    3.MCC of epidemic viral encephalitis-ARBOVIRUS




    ogilive syndrome ---acute colonic dilatation
    kasai's operation---biliary atresia
    kehr's sign---splenic atropathica
  27. samuel

    samuel New Member

    Bullet wounds skull bevelling seen

    -at inner table of entry
    -at outer table of exit wound

    Few pts about sarcoidosis. ...
    + of non caseating granulomas of multi system origin
    lung involvement + in > 90% of pts....m/c organ to be involved
    DLCO reduced, pulmonary arterial HT s/I few pts...
    lofgrens syndrome a/w hilar adenopathy, erythema nodosum and uveitis....
    pts with lofgrens a/w good prognosis in sarcoidosis
    skin manifstn s/I sarcoidosis. ..
    erythema nodosum
    maculopapular lesions
    hypo and hyper pigmentation
    keloid
    s/c nodules
    lupus pernio.....
    elevated levels of 1,25 dihydroxy vit D and ACE seen in some pts with sarcoidosis. ..
    Gallium scan findings...
    panda sign
    lambda sign....
  28. samuel

    samuel New Member

    All the muscles of soft palate are supplied by the pharyngeal branch of vagus via the pharyngeal plexus except tensor veli palatini which is supplied by mandibular br of trigeminal nerve.

    AIIMS NOV 2014
    1. Term Hara Kiri used for knife applied
    a) Over head and neck
    b) Over the abdomen
    c) Over chest and wrist
    d) Over wrist

    Answer: Over the abdomen
    Explanation:
    Hara kiri most often refers to a form of seppuku ("stomach-cutting", "abdomen-cutting").
    Seppuku is a form of Japanese ritual suicide.

    2. After post influenza infection, patient developed pneumonia. Which is causative organism?
    a) Listeria
    b) Staph aureus
    c) CMV
    d) Measles

    Answer: Staph aureus
    Explanation:
    Primary influenza virus infection may lead to lower respiratory tract symptoms, but secondary bacterial infections during and shortly after recovery from influenza virus infection are a much more common cause of pneumonia.
    Bacteria such as Staphylococcus aureus and Haemophilus influenzae are known to cause post-influenza pneumonia, but Streptococcus pneumoniae is the most prominent pathogen involved.
  29. samuel

    samuel New Member

    All the muscles of soft palate are supplied by the pharyngeal branch of vagus via the pharyngeal plexus except tensor veli palatini which is supplied by mandibular br of trigeminal nerve.

    AIIMS NOV 2014
    1. Term Hara Kiri used for knife applied
    a) Over head and neck
    b) Over the abdomen
    c) Over chest and wrist
    d) Over wrist

    Answer: Over the abdomen
    Explanation:
    Hara kiri most often refers to a form of seppuku ("stomach-cutting", "abdomen-cutting").
    Seppuku is a form of Japanese ritual suicide.

    2. After post influenza infection, patient developed pneumonia. Which is causative organism?
    a) Listeria
    b) Staph aureus
    c) CMV
    d) Measles

    Answer: Staph aureus
    Explanation:
    Primary influenza virus infection may lead to lower respiratory tract symptoms, but secondary bacterial infections during and shortly after recovery from influenza virus infection are a much more common cause of pneumonia.
    Bacteria such as Staphylococcus aureus and Haemophilus influenzae are known to cause post-influenza pneumonia, but Streptococcus pneumoniae is the most prominent pathogen involved.

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