TITBITS--1

Discussion in 'AIIMS Nov 2013' started by samuel, Aug 21, 2014.

  1. samuel

    samuel New Member

    endothelial injury---initiator of endotoxic shock
    onion bulb appearance of nerve---CIDP
    GIST___MC site stomach
    GIST___MC mesenchymal tumor
    sub endocardial hemorrhage---severe hypotension due to shock
    after intracranial damage
    death due to ectopic preg,rupture uterus,AP/PP
    hemorrhage
    arsenic poisoning
  2. samuel

    samuel New Member

    TITBITS---2

    Gallows traction: for # shaft of femur
    upto 2 yrs/12 kg
    Most imp complication is ischaemai/cyanosis of distal toes
    TB spine: dorsolumbar spine MC
    paradiscal type MC
    earliest sign reduction of disc space
    MC cause of rigid flat foot in infants and children---Congenital vertical talus
  3. samuel

    samuel New Member

    TITBITS-3

    only primary annulospiral endings are stimulated in dynamic response
    both primary and secondary endings are stimulated in static response!!
  4. samuel

    samuel New Member

    TITBITS-4

    Smooth muscle contraction:
    1.AP releases ca which binds with CALMODULIN
    2.It activates calmodulin dependant myosin light chain kinase
    3.it phosphorylates myosin light chain kinase
    PHOSPHORYLATION OF MYOSIN IS ESSENTIAL FOR CONTRACTION
  5. samuel

    samuel New Member

    #5

    dEcErEbratE----abnormal 'E'xtension
    mid collicular level transection--below red nucleus level
    also in uncal herniation
    GCS score 2 in decerebrate posturing
  6. samuel

    samuel New Member

    #6

    HURTHLE CELL CARCINOMA Vs FOLLICULAR CARCINOMA

    more often multifocal and B/L(30%)
    usually do not take up RAI
    more likely to metastasize(25%)
    higher mortality rate(20% at 10 yrs)
  7. samuel

    samuel New Member

    #7

    intersphincteric fistula---mc type fistula in ano
    coagulase negative Staph.aureus---MC cause for early onset (0-12 mo) prosthetic valve endocarditis
    Viridans Strep-----late onset(>12 mo) prosthetic valve endocarditis
    Staph aureus----native valve endocarditis and in IV drug users---acutr and vigorous infection
  8. samuel

    samuel New Member

    # 8

    Dane particle---42nm spherical virions
    1.central 27nm nucleocapsid core(HBcAg)
    2.surface-HBsAg
    HBsAg-active infection
    if present >6 mo chronic infection
    anti HBsAg previous infection
    HBcAg-not found in blood only anti HBcAg is seen
    HBeAg-indicator of viral replication
    pre core mutant-----viral replication continues but cannot be secreted)
    e Ag negative chronic hepatitis
    PCR---viral load---anti viral monitoring
  9. samuel

    samuel New Member

    #9

    alar plate-----sensory nuclei
    basal plate ----motor nuclei


    #10

    Vit K carboxylates

    1. factors 2 7 9 10
    2.protein C, S, Z
    3.bone proteins ---osteocalcin & G1a protein
    4.nerves-GAS6
  10. samuel

    samuel New Member

    #11

    periductal mastitis---hadfields operation
    comedo growth pattern---DCIS


    #13

    DUCT PAPILLOMA----not precancerous

    solitary and located under areola(4-5 cm from orifice)
    treAtment----microdochectomy
  11. samuel

    samuel New Member

    #13

    INTERNAL DIVERSION OF URINE
    * reabsorption of chloride and urea and progressive dimunition of tubular func due to pyelonephritis
    *hyperchloremic acidosis with pot. depletion
    *mild acidosis=====> osteomalacia
    *vit B12 deficiency
    *stricture
    *reflux of urine
  12. samuel

    samuel New Member

    #14

    COLITIS ASSO CARCINOMA COLON
    --from flat dysplasia
    --12% multiple synchronous CA
    --mean age 30yrs
    --uniform throughout colon
    --mucinous or anaplastic CA common

    SPORADIC CA
    --arise from adenomatous polyp
    --3 to 5% synchrpus and mltiple
    --mean age 60 yrs
    --left side predominant

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