with regard to ketamine all are true ,except

Discussion in 'AIIMS Nov 2013' started by C.Tanya, Nov 13, 2005.

  1. C.Tanya

    C.Tanya Guest

    With regard to Ketamine, all of the following are true except L :
    A) It is a direct myocardial depressant.
    B) Emergence phenomena are more likely if anticholinergic premedication is used.
    C) It may induce cardiac dysarrythmias in patients receiving tricyclic antidepressants.
    D) Has no effect on intracranial pressure.
  2. Guest

    Guest Guest

    Now this is a complicated one..
    I went through GOODMAN GILMAN thoroughly and came up with the following things:
    • Ketamine Is relatively contraindicated in increased Intracranial tension no actual mention of whether it raises ICT or not.
      Its not arrhythmogenic per se, Ketamine increases O2 consumption and is not the ideal drug for Pts at risk of Myocardial Ischemia. we know TCAs are arrythmogenic, so does this mean a patient on TCAs is at risk???
      It has direct Negative inotropic and vasodilating properties

      and its given in Tripathi that antichoniergics do cause emergence phenomeon.

    So it rules out A and B, Answer is either C Or D

    But in the vast majority of MCQ books and IN CROSS (comprehensive review of small subjects) Ketamine is said not to increase intracranial pressure.

    If someone could get reference from a standard Textbook on Anasthesia, it would be nice.
  3. Guest

    Guest Guest

    Ketamine Increases ICT

    according to Short Text Book of Anaesthesia by Ajay Yadav, (Page 78,2nd edition) Ketamine Increases ICT
  4. Guest

    Guest Guest

    Infact Ketamine increases all pressures - ICT, IOT, BP

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